Success rates among those attempting to quit are currently low, with fewer than 10% of smokers who make an attempt in any given year succeeding. A key question in tobacco control is how best to maximise the proportion of ever smokers who have quit: whether it is better to focus on increasing success rates among those who are attempting to quit or whether it would be more effective to increase the percentage of smokers trying.
There is some evidence of the value in shifting the focus from the 'quality' of smokers' quit attempts to the 'quantity' of those attempts.1 Data from California indicate that smokers on average tried 12 to 14 times before quitting for good: 12 if they used cessation aids, and 14 if they did not. These figures have stayed fairly constant since data collection began in the early 1990s, even though the availability of cessation aids has increased. The implication is that quitting aids reduce the overall number of attempts that are needed but that most smokers still have to make multiple attempts, with or without these aids. The research concluded that–while ideally, all quit attempts would involve a cessation aid, counselling or some other form of assistance–the real key to speeding up the process is to encourage smokers to keep on trying.2, 3
Expert scientific bodies have concluded that success in smoking cessation at the population level is a product of a comprehensive tobacco-control approach. This includes a combination of:4–7
Evidence-based smoking cessation treatments are underutilised. To increase demand for such treatments requires that smokers know about what is available and have access to them.8 There is evidence that many smokers are unaware of the full range of methods to quit smoking and that many use non-evidence-based approaches.9 Limited evidence also shows that current smokers may be less trusting of information sources such as health professionals or the Internet than are non-smokers,10 which may contribute to lack of use of treatments. A consumer-centred approach to this issue involves understanding and addressing smokers' needs and concerns about treatment and communicating effectively with them about the nature and value of treatments.11 Approaches to increasing the likelihood with which smokers use cessation medications may be more successful if they address expectations smokers have about their effectiveness and desirability.12 Viewing tobacco dependence as a chronic disease, and not just a habit that can be broken with willpower, is suggested by some researchers as integral to encouraging and promoting the use of effective cessation treatments to smokers.13
An integrated, comprehensive systems approach to cessation treatment and policy may help improve population quit rates.14 Treatment policies suggested in the literature include:14,15
Studies from the US modelling the impact of smoking cessation treatment policies on adult quit rates have found that implementing any policy in isolation could increase quit rates from a baseline rate of 4.3% to between 4.5% and 6%. By implementing policies in combination, the quit rate would be increased even more substantially.15
One suggested way to increase the use of available smoking cessation treatment is to give more financial support through healthcare systems on a par with other medical and behavioural disorders.16 Higher out-of-pocket expense has been associated with a lower probability of a smoker using any smoking cessation medication.17,18 There is evidence that providing access to subsidised pharmacotherapy can increase usage of quit treatments and increase the proportion of quit attempts that are successful.19,20 International research examining the long-term effects of reimbursement of smoking cessation support found that it appears to be cost-effective from a healthcare perspective.21 Evidence suggests that lower socio-economic status (SES) smokers are more addicted and may benefit from more intensive support to successfully quit, highlighting the importance of providing ready access to pharmacotherapies complemented by evidence-based behavioural support.22
UK evidence found that making non-prescription nicotine replacement therapy (NRT) smoking cessation medicines reimbursable leads to a large increase in utilisation, but does not have an impact on the number of smokers making quit attempts.23 There is evidence that adding free NRT to a smoking cessation program may increase numbers in the program and short-term quit rates, but not long-term rates.24 One study examining the impact of reduced cost NRT and a period of familiarisation with a wide range of products found no difference in quit rates at six months compared to no familiarisation.25
As mentioned above, there is evidence from the UK that making prescription smoking cessation medicines reimbursable leads to greater use, but does not affect the number of smokers making quit attempts.23
Most smokers attempt to quit on their own even though effective support methods exist. Building knowledge about and skills in quitting may play an important role in increasing successful cessation. Research suggests that smokers may be unaware of and underestimate the benefits of what is available.26 Other evidence has shown that the use of a decision aid aimed to motivate smokers to use effective cessation treatments can have a positive effect on knowledge of and attitude towards the methods, confidence about being able to quit and quit attempts but does not affect actual usage.27
To increase successful cessation at a population level it is important to understand more about the use of cessation methods by smokers and their helpfulness in the real world.28 There is evidence that going cold turkey, NRT and gradual reduction before quitting are commonly used by smokers and perceived as being very helpful, while advice from health professionals, though commonly used, is less helpful. Prescribed medication has lower use but high helpfulness.28
An important aspect of quitting is the treatment structure or level of intensity of the interventions given to help each individual smoker to quit. Measures of intensity include the length of time of each contact, total amount of contact time, and number of person-to-person sessions. Cessation rates tend to increase with extended contacts and with the number of treatment formats (different types of counselling and educational interventions).4, 29 Low intensity interventions typically offered in Australia include brief advice from a doctor or other health professional and the Quitline service, although these interventions have the potential to be more intense depending on the time and depth of information and counselling provided. In Australia, there are three types of high intensity interventions. These are the Quitline program of callbacks for smokers during their quit period, group programs that have multiple sessions, and individual counselling involving multiple sessions with a doctor, nurse or psychologist. The effectiveness of all levels of interventions is improved by concurrent use of proven quitting medications.30–33
As a general rule, the more intense the intervention, the greater the likelihood of success of cessation for any individual.4,32–34 However, higher intensity interventions are usually more costly (to the individual, government or other funder) and less likely to be available to all smokers. Therefore there will be a cost–benefit ratio for each individual method and level of intervention.
Evidence indicates that lower SES smokers are more addicted and are more likely to need more intensive support to be able to quit successfully.35
(See Sections 7.14 and 7.15 for further information)
There are two broad aspects to the question of costs and effectiveness of smoking interventions at the population level:
Both aspects are complex to estimate and information is scarce for Australia. The value of smoking cessation in comparison to other health interventions is clearly demonstrated in studies from around the world that can be extrapolated to Australia.36 Interventions that promote cessation of smoking typically cost between hundreds of dollars and several thousand dollars per life year saved, while other medical interventions more typically cost tens of thousands of dollars, making smoking cessation therapies one of the most cost-effective health interventions.37 In Australia, consulting firm Applied Economics prepared a report for the Commonwealth Department of Health and Ageing in 2003 that compared public health programs to reduce tobacco consumption, coronary heart disease, HIV/AIDS, measles and Hib-related diseases, and road trauma. For tobacco, it was concluded that for government, there was a saving of $2 for every $1 spent on tobacco-control campaigns. Based on very conservative assumptions (e.g. that Quit Campaigns were responsible for only 10% of the reduction in tobacco use) the estimated present value of overall social benefits was $8.6 billion, compared to costs of $176 million.38
The cost-effectiveness of differing approaches to smoking cessation has never been estimated for Australia, but overseas research suggests the costs per life year saved vary from a few hundred dollars for media campaigns to several thousand dollars for intensive interventions by health workers.39 One study found general practitioner (GP) training plus free quitting medication training or a combination of this approach with GP remuneration to be cost-effective, but GP training and remuneration alone to not be effective.40 The actual values depend on success rates and smoker characteristics. Since more intense interventions are more often used by more dependent smokers and those with other problems that make quitting harder, these estimates may overestimate the costs of more intensive approaches were they to be used by ordinary smokers.41 Even cross-country studies that show significant variation in cost-effectiveness of different smoking cessation medications have found results to be favourable compared to other common preventive pharmacotherapies.42
Another issue is whether children rather than adults should be the target for intervention.
There are several reasons for a broader focus, rather than concentrating on smoking prevention. School-based educational programs have generally proved to be ineffective,43 however children are positively affected by campaigns aimed at the whole community.44 Smoking cessation campaigns can reduce smoking among young people, by direct influence through exposure to the campaign, and by indirect influence through parents quitting45–47 and through the effects of making the home smokefree.48–50 In addition, a focus on cessation will bring much faster returns. Mortality from tobacco use over the next 50 years will be affected much more by the number of adults who quit than by the number of adolescents who start.51
One of the key categories of tobacco control is interventions designed to directly influence tobacco users and potential users, such as education campaigns, product warnings and provision of stop smoking services.35 The 2004–09 National Tobacco Strategy highlighted a comprehensive approach to tobacco control in Australia that included population education through increased promotion of Quit and Smokefree messages in combination with improved quality of and access to services and treatment for smokers and tailoring of messages and services to ensure access by disadvantaged groups.52
What combination of approaches to smoking cessation is likely to lead to the greatest reduction of smoking for the least cost at a population level?
Australia's National Preventative Health Strategy53 and National Tobacco Strategy52 envisage a three-level approach:
1. Zhu S-H. Differential cessation rates across populations: what explains it and how to reduce it. Smokefree Oceania. Tobacco Control Conference. From vision to reality. September, Handbook 4-7 Auckland, New Zealand, 2007.
2. Zhu S-H, Melcer T, Sun J, Rosbrook B and Pierce J. Smoking cessation with and without assistance: a population-based analysis. American Journal of Preventive Medicine 2000;18(4):305–11. Available from: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VHT-404H245-6&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ecb348482a444c60b825f507692ab2bb
3. Chapman S. Accelerating smoking cessation and prevention in whole communities. Public Health Advocacy and Tobacco Control: Making Smoking History. Blackwell Publishing, 2007;Available from: http://www.blackwellpublishing.com/contents.asp?ref=9781405161633&site=1
4. US Department of Health and Human Services. Reducing tobacco use: a report of the Surgeon General. Atlanta, Georgia: US Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2000. Available from: http://www.cdc.gov/tobacco/data_statistics/sgr/2000/complete_report/index.htm
5. World Health Organization. Policy recommendations for smoking cessation and treatment of tobacco dependence--advancing tobacco control in the 21st century. March. Geneva: World Health Organization, 2004. Available from: http://www.wpro.who.int/NR/rdonlyres/8D25E4D3-BB81-479E-8DF5-7BAF674DB104/0/PolicyRecommendations.pdf
6. Institute. NC. Monograph 12: Population based smoking cessation: proceedings of a conference on what works to influence cessation in the general population. US Department of Health and Human Services, National Institutes of Health, National Cancer Institute,, 2000.. Bethesda, MD:, 2000. Available from: http://cancercontrol.cancer.gov/tcrb/monographs/12/index.html
7. Organization WH. MPOWER: A policy package to reverse the tobacco epidemic. Geneva: 2008. Available from: http://www.who.int/tobacco/mpower/mpower_english.pdf
8. Husten C. A Call for ACTTION: Increasing access to tobacco-use treatment in our nation. American Journal of Preventive Medicine 2010;38(3 Suppl):S414–7. Available from: http://www.ajpm-online.net/article/PIIS0749379709008824/fulltext
9. Marques-Vidal P, Melich-Cerveira J, Paccaud F, Waeber G, Vollenweider P and Cornuz J. High expectation in non-evidence-based smoking cessation interventions among smokers: the Colaus study. Preventive Medicine 2011;52(3-4):258-61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21334370
10. Rutten L, Blake K, Hesse B and Ackerson L. Isolated and skeptical: social engagement and trust in information sources among smokers. Journal of Cancer Education 2011;[Epub ahead of print] Available from: http://www.ncbi.nlm.nih.gov/pubmed/21340632
11. Shiffman S. Smoking-cessation treatment utilization: The need for a consumer perspective. American Journal of Preventive Medicine 2010;38(3 suppl.):S382–4. Available from: http://www.ajpm-online.net/article/PIIS0749379709008800/fulltext
12. Vogt F, Hall S and Marteau TM. Understanding why smokers do not want to use nicotine dependence medications to stop smoking: Qualitative and quantitative studies Nicotine & Tobacco Research 2008;10(8):1405–13. Available from: http://www.informaworld.com/smpp/content~content=a901415516~db=all~order=page
13. Steinberg MB, Schmelzer AC, Lin PN and Garcia G. Smoking as a chronic disease Current Cardiovascular Risk Reports 2010;4(6):413–20. Available from: http://www.springerlink.com/content/1p754r14280tl7j4/fulltext.html
14. Abrams D, Graham A, Levy D, Mabry P and Orleans C. Boosting population quits through evidence-based cessation treatment and policy. American Journal of Preventive Medicine 2010;38(3 suppl.):S351–63. Available from: http://www.ajpm-online.net/article/PIIS0749379709008939/fulltext
15. Levy D, Graham A, Mabry P, Abrams D and Orleans C. Modeling the impact of smoking-cessation treatment policies on quit rates. American Journal of Preventive Medicine 2010;38(3 suppl.):S364–72. Available from: http://www.ajpm-online.net/article/PIIS0749379709008575/fulltext
16. Hughes J. How confident should we be that smoking cessation treatments work? Addiction 2009;104(10):1637–40. Available from: http://www3.interscience.wiley.com/user/accessdenied?ID=122538766&Act=2138&Code=4719&Page=/cgi-bin/fulltext/122538766/HTMLSTART
17. Tauras JA and Chaloupka F. The Demand for Nicotine Replacement Therapies. NBER Working Paper no. 8332. 2001. Available from: http://www.impacteen.org/fjc/PublishedPapers/w8332.pdf
18. Zeng F, Chen C, Mastey V, Zou K, Harnett J and Patel B. Utilization management for smoking cessation pharmacotherapy: varenicline rejected claims analysis. The American Journal of Managed Care 2010;16(9):667–74. Available from: http://www.ajmc.com/issue/managed-care/2010/2010-09-vol16-n09/AJMC_10sep_Zeng_667to674
19. Kaper J, Wagena EJ, Severens JL and Van Schayck CP. Healthcare financing systems for increasing the use of tobacco dependence treatment. Cochrane Database of Systematic Reviews 2005. (1)DOI: 10.1002/14651858.CD004305.pub2 Available from: http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD004305/frame.html
20. Reda A, Kaper J, Fikrelter H, Severens J and van Schayck C. Healthcare financing systems for increasing the use of tobacco dependence treatment. Cochrane Database of Systematic Reviews 2009;15(2):CD004305. Available from: http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD004305/pdf_fs.html
21. Vemer P, Rutten-van Molken M, Kaper J, Hoogenveen R, van Schayck C and Feenstra T. If you try to stop smoking, should we pay for it? The cost-utility of reimbursing smoking cessation support in the Netherlands. Addiction 2010;105(6):1088–97. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1360-0443.2010.02901.x/full
22. Siahpush M and Carlin JB. Financial stress, smoking cessation and relapse: results from a prospective study of an Australian national sample. Addiction 2006;101(1):121–7. Available from: http://www.blackwell-synergy.com/doi/abs/10.1111/j.1360-0443.2005.01292.x
23. West R, DiMarino ME, Gitchell J and McNeill A. Impact of UK policy initiatives on use of medicines to aid smoking cessation. Tobacco Control 2005;14(3):166–71. Available from: http://tc.bmjjournals.com/cgi/content/abstract/14/3/166
24. Alberg AJ, Stashefsky Margalit R, Burke A, Rasch KA, Stewart N, Kline JA, et al. The influence of offering free transdermal nicotine patches on quit rates in a local health department's smoking cessation program. Addictive Behaviours 2004;29(9):1763-78. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15530720
25. Walker N, Howe C, Bullen C, Grigg M, Glover M, McRobbie H, et al. Does improved access and greater choice of nicotine replacement therapy affect smoking cessation success? Findings from a randomised controlled trial. Addiction 2011;[Epub ahead of print] Available from: http://www.ncbi.nlm.nih.gov/pubmed/21371155
26. Hammond D, McDonald P, Fong G and Borland R. Do smokers know how to quit? Knowledge and perceived effectiveness of cessation assistance as predictors of cessation behaviour. Addiction 2004;99(8):1042–8. Available from: http://www3.interscience.wiley.com/journal/118795921/abstract
27. Willemsen MC, Wiebing M, van Emst A and Zeeman G. Helping smokers to decide on the use of efficacious smoking cessation methods: a randomized controlled trial of a decision aid. Addiction 2006;101(3):441–9. Available from: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/885/CN-00562885/frame.html
28. Hung W, Dunlop S, Perez D and Cotter T. Use and perceived helpfulness of smoking cessation methods: results from a population survey of recent quitters. BMC Public Health 2011;11(1):592. Available from: http://www.biomedcentral.com/content/pdf/1471-2458-11-592.pdf
29. Piasecki T. Relapse to smoking. Review. Clinical Psychology Review 2006;26(2):196–215. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16352382
30. Coleman T. ABC of smoking cessation. Use of simple advice and behavioural support. BMJ (Clinical Research Ed.) 2004;328(7436):397–9. Available from: http://www.bmj.com/cgi/content/full/328/7436/397
31. Le Foll B and George T. Treatment of tobacco dependence: integrating recent progress into practice. Canadian Medical Association Journal 2007;177(11):1373–80. Available from: http://www.cmaj.ca/cgi/content/full/177/11/1373
32. Fiore MC and Jaén CR. A clinical blueprint to accelerate the elimination of tobacco use. Journal of the American Medical Association 2008;299(17):2083-5. Available from: http://jama.ama-assn.org/cgi/content/full/299/17/2083
33. Fiore MC, Jaén M, Carlos Roberto, Baker TB, Bailey WC, Benowitz NL, Curry SJ, et al. Treating tobacco use and dependence. Clinical Practice Guidelines. Rockville, MD: US Department of Health and Human Services, 2008. Available from: http://www.surgeongeneral.gov/tobacco/treating_tobacco_use08.pdf
34. Ellerbeck E, Mahnken J, Cupertino A, Cox L, Greiner K, Mussulman L, et al. Effect of varying levels of disease management on smoking cessation: a randomized trial. Annals of Internal Medicine 2009;150(7):437–46. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825176/?tool=pubmed
35. Cummings KM, Fong GT and Borland R. Environmental influences on tobacco use: evidence from societal and community influences on tobacco use and dependence. Annual Review of Clinical Psychology 2009;5:433-58. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19327036
36. Ronckers ET, Groot W and Ament AJ. Systematic review of economic evaluations of smoking cessation: standardizing the cost-effectiveness. Medical Decision Making 2005;25(4):437–48. Available from: http://mdm.sagepub.com/cgi/content/abstract/25/4/437
37. Parrott S and Godfrey C. Economics of smoking cessation. BMJ (Clinical Research Ed.) 2004;328(7445):947–9. Available from: http://www.bmj.com/cgi/content/full/328/7445/947
38. Abelson P and Applied Economics. Returns on Investment in Public Health. Canberra: Department of Health and Ageing, 2003. Available from: http://www.aodgp.gov.au/internet/main/publishing.nsf/Content/19B2B27E06797B79CA256F190004503C/$File/roi_eea.pdf
39. Parrott S, Godfrey C, Raw M, West R and McNeill A. Guidance for commissioners on the cost effectiveness of smoking cessation interventions. Health Educational Authority. Thorax 1998;53(suppl. 5 Pt 2):S1–38. Available from: http://thorax.bmj.com/cgi/content/full/53/suppl_5/S1
40. Salize H, Merkel S, Reinhard I, Twardella D, Mann K and Brenner H. Cost-effective primary care-based strategies to improve smoking cessation: more value for money. Archives of Internal Medicine 2009;169(3):230–5. Available from: http://archinte.ama-assn.org/cgi/reprint/169/3/230
41. Godfrey C, Parrott S, Coleman T and Pound E. The cost-effectiveness of the English smoking treatment service: evidence from practice. Addiction 2005;100(Suppl 2):70–83. Available from: http://www.ingentaconnect.com/content/bsc/add/2005/00000100/A00201s2/art00008;jsessionid=6992a2bm37073.alice?format=print
42. Cornuz J, Gilbert A, Pinget C, McDonald P, Slama K, Salto E, et al. Cost-effectiveness of pharmacotherapies for nicotine dependence in primary care settings: a multinational comparison. Tobacco Control 2006;15(3):152-159. Available from: http://tc.bmjjournals.com/cgi/content/abstract/15/3/152
43. Thomas R and Perera R. School-based programmes for preventing smoking. Cochrane Database of Systematic Reviews.2006. (3)DOI: 10.1002/14651858.CD001293.pub2 Available from: http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD001293/frame.html
44. White V, Tan N, Wakefield M and Hill D. Do adult focused anti-smoking campaigns have an impact on adolescents? The case of the Australian National Tobacco Campaign. Tobacco Control 2003;12(suppl 2):ii23-29. Available from: http://tobaccocontrol.bmj.com/cgi/content/abstract/12/suppl_2/ii23
45. Farkas A, Distefan J, Choi W, Gilpin E and Pierce J. Does parental smoking cessation discourage adolescent smoking? Preventive Medicine 1999;28(3):213–8. Available from: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WPG-45FJWWP-5B&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=4e43cf2570abb2ae15af7cecabb3b763
46. Bricker J, Leroux B, Peterson A, Kealey K, Sarason I, Andersen M, et al. Nine-year prospective relationship between parental smoking cessation and children's daily smoking. Addiction 2003;98(5):585 – 93. Available from: http://www.blackwell-synergy.com/doi/full/10.1046/j.1360-0443.2003.00343.x
47. den Exter Blokland E, Engels R, Hale W, Meeus W and Willemsen M. Lifetime parental smoking history and cessation and early adolescent smoking behavior. Preventive Medicine 2004;38(3):359–68. Available from: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WPG-4BBVVRG-4&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_version=1&_urlVersion=0&_userid=10&md5=ad2e0c0a133059a211410041668c32da
48. Scollo M. Towards an Australian national policy for the treatment of dependence on tobacco-delivered nicotine. Melbourne: VicHealth Centre for Tobacco Control, 2003.
49. Szabo E, White V and Hayman J. Can home smoking restrictions influence adolescents' smoking behaviors if their parents and friends smoke? Addictive Behaviors 2006;31(12):2298-303.
50. Clark P, Schooley M, Pierce B, Schulman J, Hartman A and Schmitt C. Impact of home smoking rules on smoking patterns among adolescents and young adults. Preventing Chronic Disease 2006;3(2):A41. Available from: http://www.cdc.gov/pcd/issues/2006/apr/05_0028.htm
51. Peto R, Darby S, Deo H, Silcocks P, Whitley E and Doll R. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of statistics with two case-control studies. BMJ (Clinical Research Ed.) 2000;321(7257):323–9. Available from: http://www.bmj.com/cgi/reprint/321/7257/323
52. Ministerial Council on Drug Strategy. Australian National Tobacco Strategy 2004-2009. Canberra: Department of Health and Ageing, 2005. Available from: http://www.health.gov.au/internet/wcms/publishing.nsf/Content/phd-pub-tobacco-tobccstrat2-cnt.htm
53. National Preventative Health Taskforce. Australia: the Healthiest Country by 2020. Technical Report No 2 Tobacco Control in Australia: making smoking history. Canberra: Department of Health and Ageing, 2009. Available from: www.health.gov.au/internet/preventativehealth/.../tobacco-cover.pdfSimilar