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18.11 Cessation interventions to help people quit vaping
Foreword

Relevant news and research: Cessation interventions to help people quit vaping

Barnes, L. A. J., Longman, J., Gersh, V. L., Druitt, S., Bonevski, B., Paul, C., Adams, C. and Passey, M. (2025). Australian women's perspectives on preventing postpartum relapse or quitting smoking or vaping in the postpartum year. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41189413


Booth, K., Bryant, J., Maddox, R., Ridgeway, T., Maidment, S., Martiniuk, A. L., Chamberlain, C., Eades, S. J., Burchill, L. J., Belfrage, M., Bennett, J., Doran, C., Collis, F., Mills, Z., Foster, J., Mersha, A. G., Roberts-Barker, K., Oldmeadow, C., Longbottom, H., Wills, K., Taylor, N. and Kennedy, M. (2025). Which way? Group-based smoking and vaping cessation support for Aboriginal and Torres Strait Islander women: protocol for a non-randomised type 1 hybrid implementation study. BMJ Open, 11, e097875. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41271414


Butler, A. R., Lindson, N., Livingstone-Banks, J., Notley, C., Turner, T., Rigotti, N. A., Fanshawe, T. R., Begh, R., Wu, A. D., Brose, L., Conde, M., Simonavicius, E. and Hartmann-Boyce, J. (2025). Interventions for quitting vaping. Cochrane Database Syst Rev, 11, CD016058. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41288132


Doggrell, S. A. (2025). Does varenicline promote abstinence in youths who vape?. Expert Opin Pharmacother, 1-4. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41265873


Graham, A. L., Cha, S., Do, E. K., Jacobs, M. A., Edwards, G. and Papandonatos, G. D. (2025). Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation. Subst Abuse Treat Prev Policy, 1, 48. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41177894


Martins, S. R., Correa, P., Costa, C., Sousa, M. G., Tourinho, C. A. P. and Borges, V. L. G. (2025). Vaping cessation: how to treat nicotine dependence and tailor the nicotine replacement dose. A narrative review. J Bras Pneumol, 4, e20250061. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41172410


Masonbrink, A. R., Bae, D., Cho, J., Miech, R. A., Dai, H. D., Harlow, A. F., Sussman, S., Han, D. H., Sanchez, L. M., Adjei, A., Meza, L. R., Li, M. and Leventhal, A. M. (2025). Trends in Daily Nicotine Vaping and Unsuccessful Quit Attempts in Youths. JAMA Netw Open, 11, e2541061. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41182763


Morean, M. E., Ouellette, R. R., Li, W. and Sharma, A. (2025). Psychometric properties of the Nicotine E-cigarette Withdrawal Scale for use with adults. Drug Alcohol Depend, 112968. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41260026


Vasooja, D., Peters, K., Wasan, D., Najafi, E., Warnapala, M., Baker, Y. and Martinez-Jimenez, M. (2025). GPs' perspectives on assessing adolescent vaping among individuals without prior smoking history: a qualitative study within primary care. BJGP Open. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41253488


Bhadania, M., Yadav, S., Mathur, A., Acharya, A. and Mehta, V. (2025). Mapping the effectiveness of digital health interventions in promoting electronic cigarette cessation: a systematic review and meta-analysis of randomized controlled trials. BMC Public Health, 1, 3645. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41152828


Fonteyne, K., Keys, E., Hasan, K. and Struik, L. (2025). Exploration of Digital Interventions for Vaping Cessation: Scoping Review. J Med Internet Res, e76983. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41129808


Gonzalez, I. (2025). The Harms of Vaping: How Clinicians Can Help Patients Quit. Arch Bronconeumol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41062394


Haug, S., Caputo, L., Wenger, A., Kiselev, N., Studhalter, O. and Schaub, M. P. (2025). WhatsApp-Based Coaching Program to Support Smoking and Vaping Cessation Among Young People: Pre-Post Study on Acceptance and Preliminary Efficacy. JMIR Mhealth Uhealth, e65301. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41037757


Maidment, S., Ridgeway, T. L., Booth, K., Collis, F., Bryant, J., Foster, J., Mills, Z. and Kennedy, M. (2025). Identifying and integrating Behaviour Change Techniques into an Indigenous-led group based smoking and vaping cessation program for women during pregnancy and the perinatal period: upholding Indigenous knowledges and rights in research. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41147774


Ding, R., Cook, S., Stone, P. W., Srirathan, D., Shyam, Y., Anand, R., Sudharshan, P. and Quint, J. K. (2025). Systematic Review and Development of Recommended Code Lists to Identify Smoking and Vaping Status in Electronic Health Records (EHR). Clin Epidemiol, 753-764. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40948904


Heshmati, J., Bates, E. L., Shahen, S., Walker, K. L., Pipe, A., Mullen, K. A. and Mir, H. (2025). Patterns of E-Cigarette Use Among Cardiac Inpatients at a Tertiary-Care Hospital: A Cross-Sectional Survey. CJC Open, 8, 1083-1092. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40894853


Hoo Chuin Shen, M., Gabriel, M. M., Brennan, L. and Isba, R. (2025). Interventions delivered in healthcare settings to promote vaping cessation in children and young people (under the age of 18 years): a scoping review protocol. BMJ Open, 9, e102261. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40921637


Le, D., Saba, M., Dan, E., Bussing, J., Bittoun, R., Shah, S. and Saini, B. (2025). No-To-Nicotine: Developing and Evaluating a Smoking and Vaping Cessation Module for Pharmacy Students. Am J Pharm Educ, 101864. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40947021


Sobral, M. V. S., de Melo Neto, A. P., Menechini, R. B., da Cunha Pirolla, R., Marcal, J. B. C. and Acuia, T. A. S. (2025). Efficacy and safety of varenicline for electronic cigarette cessation: A systematic review and meta-analysis. Drug Alcohol Depend, 112884. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40961623


Tiffen, L., Sund, L. J., Kennedy, C., Hollands, M., Dargan, P. I. and Wood, D. M. (2025). Assessment of vaping and substance use documentation in the emergency department and acute medical unit. Emerg Med J. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40987547


Tran, T. P. T., Tran, C., Ling, P. M., Popova, L. and Nguyen, N. (2025). Applying Human-Centered Design to Develop Smartphone-Based Intervention Messages to Help Young Adults Quit Using E-Cigarettes and Cigarettes: A Remote User Testing Study. JMIR Hum Factors, e76503. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40965202


Zhang, Y. and Wang, Y. (2025). E-cigarette or vaping product use-associated lung injury outbreak and public perceptions and trends in smoking cessation discussions on Twitter. PLoS One, 9, e0332414. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40966222


Bauer, S. E., Macrea, M., Casey, A., Dagli, E., Eakin, M. N., Farber, H. J., Gonzalez, P., Hayes, D., Jr., Hu, S. W., Kathuria, H., Knight, S. L., Moraes, T. J., Neptune, E. R., Piper, M. E., Skeen, E. H., Ueng, C. S., Upson, D., Walley, S. C. and Rao, D. R. (2025). Treatment of Nicotine Use in Adolescents Under 18 Years of Age: An Official American Thoracic Society Clinical Practice Guideline. Am J Respir Crit Care Med, 9, 1584-1599. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40879357


Dowling, J. (2025). First vaping addiction treatment approved in Australia. The Australian,  ,  . Available from: https://www.theaustralian.com.au/health/medical/first-vaping-addiction-treatment-approved-in-australia/news-story/1dd6809763f3f4657c337e3ba0c3e344?btr=7b5f2d222cac75dbf534fb6b224d8e93


Evins, A. E., Levy, S. and Schuster, R. (2025). Varenicline for Youth Nicotine Vaping Cessation-Reply. JAMA. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40875242


Lockett, C., Thorpe, A., Stockings, E., Jongenelis, M., Vandeleur, M. and Shah, S. (2025). E-cigarette use in adolescents: prevention and cessation strategies from an Australian community of practice. Aust N Z J Public Health, 4, 100264. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40774151


Pei, Y. (2025). Varenicline for Youth Nicotine Vaping Cessation. JAMA. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40875202


Rabade-Castedo, C., Cristobal-Fernandez, M., de Granda-Orive, J. I., Luhning, S., Pacheco-Gallego, M. C., Regalado-Pineda, J., Thirion-Romero, I., Blanquicett-Barrios, L. D. C., Medin, M. I., Buljubasich, D., Ramos-Pinedo, A., Gorordo-Unzueta, I., Frino-Garcia, A., Pastor-Espla, E., Canon-Barroso, L., Francisco-Corral, G., Sandoval-Contreras, R., Riesco-Miranda, J. A., Borrajo, M. C., Moran, A., Hernandez-Perez, M. A., Perez-Padilla, J. R., Diaz-Santos, G. A. and Jimenez-Ruiz, C. A. (2025). Consensus Document SEPAR-AAMR-ALAT-ASONEUMOCITO-SMNCT on Assessment and Treatment for Consumers of New Tobacco and Nicotine Products. Arch Bronconeumol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40784851


Sakhuja, M., Farris, S., Queen, T. L., Hall, M. G., Kalan, E., Sheeran, P., Ribisl, K. M. and Brewer, N. T. (2025). Longitudinal correlates of quitting e-cigarettes in the United States. Prev Med Rep, 103197. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40821920


Pravosud, V., Ling, P. M., Halpern-Felsher, B. and Gribben, V. (2025). Adolescents' Interest in Quitting Nicotine or Cannabis E-Cigarettes. Clin Pediatr (Phila), 9.92283E+13. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40684359


Robertson, J. (2025). Boots pharmacies launch pilot stop vaping service. The Pharmaceutical Journal. Available from:


Starnini, J. G., Natalello, G., Nigroli, F., Diana, C., Bargagli, E. and Melani, A. S. (2025). Electronic Nicotine Delivery Systems (ENDS): Implications for the Clinician. Pulm Ther. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40658320


Whaley, R. C., Harlow, A. F., Galimov, A., Tran, D. D. and Barrington-Trimis, J. L. (2025). Methods for Vaping Cessation Among Young Adults in Southern California. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40684797


Williams, B. S., Kaye, J. T., Conner, K. L., Bird, J., Adsit, R. and Piper, M. E. (2025). Wisconsin Adolescents' Attitudes, Beliefs, Motivations, and Behaviors Surrounding E-Cigarette Use and Cessation. WMJ, 2, 144-147. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40690634


Graham, A. L., Cha, S., Jacobs, M. A., Edwards, G., Funsten, A. L. and Papandonatos, G. D. (2025). Adverse Childhood Experiences are Associated With e-Cigarette Abstinence in a Vaping Cessation Randomized Clinical Trial Among Adolescents. J Adolesc Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40459484


Merreighn, T., Veilleux, J. C., Schisler, E. D., Tabassum, M. and Dobbs, P. D. (2025). The experiences of young adults attempting to quit e-cigarettes: A mixed-methods analysis. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40503162


Zhou, F., Warren, J. and Goodyear-Smith, F. (2025). Vaping and smoking in adolescents 14 and under in Aotearoa New Zealand: cross-sectional study of e-screening data. J Prim Health Care, 2, 101-107. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40577207


Heffner, J. L., Baker, K., Georgiou, K., Graham, A. L., Kelly, M. M., Konstantinou, P., Lamprou, E., Lele, C., Lok, K. Z., Orzechowski, M., Ruiz, R. A., Serfozo, E. and Karekla, M. (2025). ACT on Vaping: Pilot Randomized Controlled Trial of a Novel Digital Health App with Text Messaging for Young Adult Vaping Cessation. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40411791


Heshmati, J., Mullen, K. A., Quirouette, E., Bernick, J., Pipe, A. and Mir, H. (2025). Patterns of e-cigarette use and interest in cessation among current users in Ontario: An online cross-sectional study. PLoS One, 5, e0322736. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40343895


Langley, R. J., Hamilton, H., Turner, S., Watt, E., Posner, F. and Macleod, K. A. (2025). E-Cigarette Education and Training in Medical Schools: A National Survey. Pediatr Pulmonol, 5, e71125. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40365934


Long, L. J., Samora, J., Indriolo, T., Huber, E. G., Geng, Y., Ouyang, L., Papini, S., Smits, J. A. J. and Otto, M. W. (2025). Examining the individual and combined influence of negative affect and nicotine cue provocation on craving to vape nicotine among e-cigarette users. Addict Behav, 108378. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40382978


Marshall, H., Vandeleur, M., Dean, E., Barton, C., Luxton, N., Carson-Chahhoud, K., Schultz, A., Williams, J., Grammatopoulos, T., Stone, E., Shah, S., Jones, S., McDonald, C. F. and Peters, M. (2025). Thoracic Society of Australia and New Zealand (TSANZ) Guidance for the Management of Electronic Cigarette Use (Vaping) in Adolescents and Adults. Respirology. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40432493


Palmer, A. M., DeMass, R., Rojewski, A. M., Bagley, E. M., Carpenter, M. J., Smith, T. T. and Toll, B. A. (2025). Augmented Doses of Nicotine Replacement Therapy: Feasibility for Dual Cigarette and E-cigarette Cessation. Am J Prev Med, 107664. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40409566


Subramanian, R., Samson, K. and Dai, H. D. (2025). Tobacco control messages for individuals who use both cigarettes and e-cigarettes: a randomised trial comparing biomarker outcome with cessation experience narratives. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40335266


Tran, T. P. T., Nguyen, T. T., Nguyen, T. N. P., Tran, T. T. H., Phan, V. C., Luong, N. K., Phan, T. H., Duong, T. A., Hoang, V. M. and Weaver, S. R. (2025). The prevalence and predictors of vaping quit attempt among electronic cigarette users: findings from provincial version of Global Adult Tobacco Survey 2020 in Vietnam. BMC Public Health, 1, 1651. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40325443


Borrelli, B., Weinstein, D., Endrighi, R., Ling, N., Koval, K., Quintiliani, L. M. and Konieczny, K. (2025). Virtual Reality for the Prevention and Cessation of Nicotine Vaping in Youth: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40278000


Evins, A. E., Cather, C., Reeder, H. T., Evohr, B., Potter, K., Pachas, G. N., Gray, K. M., Levy, S., Rigotti, N. A., Iroegbulem, V., Dufour, J., Casottana, K., Costello, M. A., Gilman, J. M. and Schuster, R. M. (2025). Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial. JAMA. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40266580


Rodberg, D., Nawara, R., Taylor, M. and Struik, L. (2025). User Perceptions of E-Cigarette Cessation Apps: Content Analysis of App Reviews. J Med Internet Res, e59997. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40233344


Tran, D. D., Davis, J. P., Buch, K., Leventhal, A. M., Ewing, S. W. F. and Pedersen, E. R. (2025). A novel online vaping intervention and smoking prevention program for young adults who vape: protocol for a randomized controlled trial. Addict Sci Clin Pract, 1, 36. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40259422


Truth Initiative (2025). Truth Initiative and Blip Join Forces to Make Quitting Nicotine Easier for Young Adults. . Available from: https://truthinitiative.org/press/press-release/truth-initiative-and-blip-join-forces-make-quitting-nicotine-easier-young


Maday, E., Brekke, A., Li, J. and Abraham, O. (2025). Pharmacists' Perspectives on Providing Educational Intervention to Address E-Cigarette Use and Vaping among Adolescents and Their Parents. J Am Pharm Assoc (2003), 102392. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40139390


Park, K., Kim, D. B., Shin, J. Y., Nam, C. M. and Park, E. C. (2025). Association between type of smoking and smoking cessation plans in Korean adults: A nationwide cross-sectional study. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40026694


Whaley, R. C., Unger, J. B., Harlow, A. F., Barrington-Trimis, J. and Galimov, A. (2025). Blip World: nicotine replacement therapy for Gen Z?. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40157745


D'Esterre, A. P., Tulsiani, S., Hair, E. C., Aseltine, M., Yu, L. Q., Ichimiya, M., Bingenheimer, J. B., Cantrell, J. and Evans, W. D. (2025). Pathway from Exposure to an E-Cigarette Prevention Social Media Campaign to Increased Quitting Intentions: A Randomized Trial Among Young Adult E-Cigarette Users. Int J Environ Res Public Health, 2. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40003532


Heshmati, J., Pandey, A., Benjamen, J., Furqan, M., Salman, M., Visintini, S., Mullen, K. A., Guyatt, G., Pipe, A. L. and Mir, H. (2025). Vaping cessation interventions: a systematic review and meta-analysis. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40011054


Jebai, R., Hong, T., Ranker, L. R., Wu, J., Rohila, A., Fetterman, J. L. and Cornacchione Ross, J. (2025). Social Media Engagement and Quit Intentions among Youth with Exclusive E-cigarette Use: The Moderating Role of Social Norms. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39912206


Krienke, M. and Fuest, S. (2025). EBM BLS: Varenicline Improves Electronic Cigarette Quit Success Rate. J Gen Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40016378


NSW Health Minister Ryan Park (2025). App to support youth off vapes while tens of thousands of illegal products removed from community. . Available from: https://www.nsw.gov.au/ministerial-releases/app-to-support-youth-off-vapes-while-tens-of-thousands-of-illegal-products-removed-from-community


Solano, L. (2025). Evidence-based treatment approaches for adolescent electronic cigarette use. JAAPA, 3, 22-29. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39903096


Acosta-Penaloza, J. S., Geletko, K. W. and Mills, J. (2025). Demographic Characteristics Associated With Adolescent Receipt of Provider E-Cigarette Screening and Advice and the Impact on Harm Perception. AJPM Focus, 1, 100309. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39866160


Carrillo, M., Yingst, J., D'Souza, G. C., Dahal, S., Allen, S. I. and Foulds, J. (2025). Interest in Quitting and Utilizing Quitline Services Among Long-Term E-Cigarette Users. Subst Use Misuse, 1-Jul. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39781624


Wooten, S., Catley, D., Miller, M. K., Wilson, K., Richter, K. P. and Masonbrink, A. (2025). Treatment of e-cigarette use among hospitalised adolescents and young adults: a protocol for intervention development and evaluation of preliminary efficacy and implementation outcomes in a randomised controlled trial. BMJ Open, 1, e094323. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39779271


Public Health Services (2024). Guide to Supporting Young People to Quit E-cigarettes. . Available from: https://www.health.tas.gov.au/sites/default/files/2024-08/guide_to_supporting_young_people_to_quit_e-cigarettes.pdf


Ruzlin, A. N. M., Abdullah, N. N. and Tangiisuran, B. (2024). Empowering general practitioners to assist smoking cessation among combustible and e-cigarette users effectively: A dual challenge in Malaysia. Aust J Gen Pract, 12, 959-960. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39628024


Vickerman, K. A., Carpenter, K. M., Mullis, K., Shoben, A. B., Nemeth, J., Mayers, E. and Klein, E. G. (2024). Quitline-Based Young Adult Vaping Cessation: A Randomized Clinical Trial Examining NRT and mHealth. Am J Prev Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39665734


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2