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18.6.2 Health effects of e-cigarette use during adolescence
Foreword

Relevant news and research: Health effects of e-cigarette use during adolescence

Hackworth, E. E., Vidana-Perez, D., O'Neal, R., Kim, M., Fillo, J., Hammond, D. and Thrasher, J. F. (2025). The Association Between Adolescent Mental Health Symptoms and Characteristics of Cigarette and E-Cigarette Use. Subst Use Misuse, 1-10. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41250305


Sullivan, R. M., Wallace, A. L., May, A. C., Lyman, J. K., Lisdahl, K. M., Wade, N. E., Courtney, K. E., Doran, N. and Jacobus, J. (2025). Early nicotine initiation and white matter integrity: Associations from late childhood to mid-adolescence. Drug Alcohol Depend, 112954. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41242147


Taillieu, T. L., Salmon, S., Fortier, J., Stewart-Tufescu, A., Osorio, A., MacMillan, H. L., Sareen, J., Tonmyr, L., Brownell, M. and Afifi, T. O. (2025). Cross-sectional and longitudinal associations between adolescent vaping and physical and mental health problems. Addict Behav Rep, 100633. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41210908


Delshad, S., Abbasi, M. F., Geraminia, N., Rohani, E., Vafaee, F., Taheri, F., Soti, M., Sheibani, V. and Sabzalizadeh, M. (2025). Tactile learning and memory deficits following cigarette and e-cigarette exposure: neural alterations in the barrel cortex and hippocampus. Cogn Process. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41123808


Sawyer, S. M., Canterford, L., Greenhalgh, E., Ellul, S., Vijayakumar, N., Scollo, M. and Dashti, S. G. (2025). Tracking the course of vaping and cigarette smoking across adolescence: the Child to Adult Transition Study. The Lancet Regional Health – Western Pacific. Available from: https://doi.org/10.1016/j.lanwpc.2025.101719


Corsello, A., Ferraro, V. A., Reali, L., Venditto, L., Spatuzzo, M., Di Cicco, M. E., Ghezzi, M., Indinnimeo, L. and La Grutta, S. (2025). Novel nicotine and tobacco products in pediatric age: a joint position paper. Ital J Pediatr, 1, 270. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40993785


Happer, J. P., Courtney, K. E., Baca, R. E., Andrade, G., Shen, Q., Liu, T. T. and Jacobus, J. (2025). Age of onset of nicotine use and severity of nicotine addiction symptoms are associated with hippocampal volume in late adolescents and emerging adults. Front Adolesc Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40959117


Khodaee, A., Reed, A. and Khodaee, M. (2025). Electronic Cigarette Use (Vaping) Among Adolescents: A Narrative Review of an Emerging Public Health Epidemic. Cureus, 8, e89422. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40918883


Lin, J. and Ma, C. (2025). The hidden threat of tobacco use among Chinese adolescents. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41019461


Sheikhattari, P., Barsha, R. A. A., Egboluche, C. and Assari, S. (2025). Electronic and Conventional Cigarette Use and Academic Achievement Among Predominantly Low-Income Black High School Students. Children (Basel), 9. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41007102


Vicente, A., Neves, L. and Leao, T. (2025). Addressing the Risks of the New Tobacco Product Wave in Portugal. Acta Med Port. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40938151


Golder, S., Hartwell, G., Barnett, L. M., Nash, S. G., Petticrew, M. and Glover, R. E. (2025). Vaping and harm in young people: umbrella review. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40829950


Gomes, M. N., Reid, J. L., Taylor, E. V., Edwards, R., O'Connor, R., Hyland, A. and Hammond, D. (2025). E-cigarette consumption among youth who vape in Canada, England, New Zealand and the USA: Exploring methods to quantify consumption amounts and differences by product attributes using population-level surveys. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40780823


VanFrank, B., Williams, T. R., Alcantara, I. C., Hertz, M., Al-Shawaf, M., Meyers, C. and West, A. (2025). E-Cigarette Use and Symptoms of Depression and Anxiety Among US Middle and High School Students. Prev Chronic Dis, E51. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40815093


de Miranda Schmitz, B., de Miranda Schmitz, F., Prazeres, G. B. and Marchioni, C. (2025). Major pulmonary clinical manifestations of e-cigarette use by adolescents: a scoping review. Respir Med, 108281. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40738371


Iturralde, K., Boparai, K., Veldhuizen, S., Selby, P. and Zawertailo, L. (2025). Attentional bias in young adult tobacco cigarette smokers and e-cigarette users: an eye-tracking study. Psychopharmacology (Berl). Available from: https://www.ncbi.nlm.nih.gov/pubmed/40719855


Kim, S. and Selya, A. (2025). Persistence of Youth Use of Electronic Nicotine Delivery Systems in the Population Assessment of Tobacco and Health, 2017-2021. Subst Use Misuse, 1-Jul. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40588352


Li, W., Kalan, E., Jebai, R., Kondracki, A. J. and Osibogun, O. (2025). Is vaping e-cigarettes associated with sleep duration in US young adults? evidence from the 2022 BRFSS. Sleep Breath, 4, 248. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40679707


Roberts, M. E., Lu, B., Wijewantha, Y., Singer, J. M., Wagner, D. D., Klein, E. G., Wold, L. E., Wagener, T. L. and Tackett, A. P. (2025). Real-Time Evaluation of Craving, Withdrawal, and Respiratory Symptoms Among Adolescents and Young Adults Who Use e-Cigarettes. Subst Use Misuse, 1-Jul. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40643981


Sheikhattari, P., Barsha, R. A. A., Egboluche, C. and Assari, S. (2025). Use of Electronic and Conventional Cigarettes and Self-Rated Mental Health in High School Students. Children (Basel), 7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40723095


Castro, M., Prestes, L. M., Souza, G. A. B., Hanel, M. P. C., Pinto, L. A. and Silva, D. (2025). An overview of electronic cigarette use and consequences among adolescents. J Bras Pneumol, 2, e20250137. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40531741


Haque, S. and Saldanha, N. (2025). An update on nicotine use in adolescents. Curr Probl Pediatr Adolesc Health Care, 101753. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40579268


Jackson, S. E., Brown, J., Tattan-Birch, H. and Jarvis, M. J. (2025). Changing patterns of nicotine product use and nicotine dependence among United States high-school students: The National Youth Tobacco Survey, 2014-2023. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40557691


Isba, R., Brennan, L., Lunn, J. and Brewster, L. (2025). Vaping-associated nicotine dependence among children and young people in the United Kingdom: time to act. Perspect Public Health, 2, 73-75. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40364595


Souza, I. N. O., Balerio, G. N., Pandy, V., Grilli, M. and Neves, G. A. (2025). Editorial: World No-Tobacco: effects of tobacco and nicotine on the brain. Front Pharmacol, 1610178. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40395725


Cho, J., Harlow, A. F., Leventhal, A. M., Pentz, M. A., Bae, D., Han, D. H., McConnell, R., Eckel, S. P. and Barrington-Trimis, J. L. (2025). Longitudinal patterns of e-cigarette use initiation and progression to frequent vaping from mid-to-late adolescence to young adulthood. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40176499


Boparai, K., Lin, H. Y., Selby, P. and Zawertailo, L. (2025). Grey matter morphometry in young adult e-cigarette users, tobacco cigarette users & non-using controls. Neuropsychopharmacology. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40102267


Cho, J., Miech, R. A., Harlow, A. F., Han, D. H., Dai, H. D., Sussman, S. and Leventhal, A. M. (2025). Nicotine Concentration of E-Cigarettes Used by Youths. JAMA Netw Open, 3, e252215. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40146111


Hammond, D., Reid, J. L., Goniewicz, M. L., McNeill, A., O'Connor, R. J., Corsetti, D., Block, A. C., Brose, L. S. and Robson, D. (2025). Nicotine Exposure From Smoking Tobacco and Vaping Among Adolescents. JAMA Netw Open, 3, e2462544. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40072439


Hanewinkel, R. and Hansen, J. (2025). Adolescent cigarette and e-cigarette use after the rise of disposable e-cigarettes: interrupted time series study in Germany 2016-2024. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40089308


Birur, S., Burk, B. G., Fargason, R. E., Alhassan, A. and Reddy, A. (2025). Exploring the Interplay of Sleep and Nicotine Vaping in Adolescents: An Evidence-Based Narrative Review. Psychopharmacol Bull, 2, 60-74. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39935668


Brookfield, S., Chye, N. A., Carah, N. and Gartner, C. (2025). Reporting on the "Next Generation of Nicotine Addicts": A Mixed-Methods Analysis of How the Australian Media has Covered and Constructed Youth Vaping (2018-2023). Health Commun, Jan-14. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39931894


Department of Health and Social Care, Ashley Dalton MP and The Rt Hon Wes Streeting MP (2025). 10-year study to shed light on youth vaping. . Available from: https://www.gov.uk/government/news/10-year-study-to-shed-light-on-youth-vaping


Hoek, J., Hosking, R., Graham-DeMello, A., Sanders, C., Teddy, L., Ball, J., van der Eijk, Y. and Gallopel-Morvan, K. (2025). Removing or returning freedom? Views on a nicotine-free generation policy held by young people from aotearoa who use electronic nicotine delivery systems (ENDS). Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39904629


Lee, S. and Seo, D. C. (2025). Longitudinal Behavioral Transitions in Adolescent Electronic Nicotine Delivery Systems Use: Markov Multistate Transition Model. J Adolesc Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39927914


McCabe, S. E., Pasman, E., Wilens, T., Boyd, C. J., Veliz, P., McCabe, V., Chen, B., Dickinson, K. and Evans-Polce, R. J. (2025). Attention-Deficit/Hyperactivity Disorder Symptoms and Later E-Cigarette and Tobacco Use in US Youths. JAMA Netw Open, 2, e2458834. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39932711


McMaine, T. and Kolokythas, A. (2024). Response to Letter to the Editor regarding Editorial on e-cigarettes and brain development. Oral Surg Oral Med Oral Pathol Oral Radiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39890470


Tebay, V., Ratang, W., Ohoiwutun, Y. and Muttaqin, M. Z. (2025). E-Cigarettes in the Young Generation and Future Health Risks in Indonesia. Subst Use, 29768357251318556. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39959713


Toledo, J. P. C. (2025). Vaping illusions: The hidden risks of E-cigarette use among young Filipinos and adolescents in Latin America. Int J Cardiol Cardiovasc Risk Prev, 200375. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40007582


Hackworth, E. E., Vidana-Perez, D., O'Neal, R., Kim, M., Fillo, J., Hammond, D. and Thrasher, J. F. (2025). Trends in Mental Health Symptoms, Nicotine Product Use, and their Association Over Time Among Adolescents in Canada, England, and the US: Findings from the ITC Adolescents Tobacco and Vaping Survey, 2020-2023. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39820468


Kundu, A., Sanchez, S., Seth, S., Feore, A., Sutton, M., Sachdeva, K., Abu-Zarour, N., Chaiton, M. and Schwartz, R. (2025). Evidence update on e-cigarette dependence: A systematic review and meta-analysis. Addict Behav, 108243. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39826373


Kurniawan, A. V., Amtha, R., Gunardi, I., Heriandi, A. and Sari, E. F. (2025). The Impact of Electronic and Conventional Cigarette Use towards Saliva Profile and Oral Microbiota in Adolescents. Asian Pac J Cancer Prev, 1, 309-318. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39874014


Graham-DeMello, A., Sanders, C., Hosking, R., Teddy, L., Ball, J., Gallopel-Morvan, K., van der Eijk, Y., Hammond, D. and Hoek, J. (2024). Lived experiences of stigma and altered self-perceptions among young people who are addicted to ENDS: a qualitative study from Aotearoa New Zealand. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39622641


Parks, M. J., Arterberry, B. J. and Patrick, M. E. (2024). Vaping-specific nicotine dependence across days among a national sample of US young adults who vape. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39657709


Sun, R. and Yi, N. (2024). Early onset of e-cigarette use and subsequent use frequency among US high school students. Prev Med Rep, 102935. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39659809


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2