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18.6.7 E-cigarette use and oral health
Foreword

Relevant news and research: E-cigarette use and oral health

Abdulhay, N., Wiener, R. C., Wen, S., Gibbs, B. B. and Bhandari, R. (2026). Longitudinal Analysis of Tobacco Use and Oral Health in Adolescents: Findings From the Population Assessment of Tobacco and Health Study. J Adolesc Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41823930


Alcheva, A., Jensen, J. A., Hatsukami, D. K. and Stepanov, I. (2026). Changes in the oral microbiota after switching from smoking to exclusive e-cigarette use in an 8-week product-switching trial. Cancer Prev Res (Phila). Available from: https://www.ncbi.nlm.nih.gov/pubmed/41873129


de Carvalho Faria, N., Carvalho, B., Alves, M. G. O., Feitosa Lima, I., Iwai, L. K., Salardani, M., Zelanis, A. and Almeida, J. D. (2026). Salivary Proteomics Reveals Oxidative Markers in E-Cigarette Users. J Proteome Res, 4, 1846-1854. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41801104


Elena, C., Stefano, C., Marina, D., Pinar, E. and Nikolaos, D. (2026). Tobacco Smoking and Smoke-Free Products as Risk Factors for Dental Implants: A Systematic Review. Clin Oral Implants Res, 3, 262-286. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41776304


La Rosa, G. R. M., Samaranayake, L. P., Zaura, E., Sun, A., Fuochi, V., Furneri, P. M., Kowalski, J., Myszel, K., Chapple, I. and Polosa, R. (2026). Impact of Electronic Cigarette Use on the Oral Microbiota: A Systematic Review. J Clin Periodontol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41856754


Ramasamy, P., Kandaswamy, K., Navaneethan, R. and Subramanian, R. (2026). E-cigarette aerosol exposure drives extracellular matrix gene dysregulation and collagen remodeling in gingival fibroblasts: An in vitro study. J Oral Biol Craniofac Res, 2, 101428. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41768314


Bangiev, L., Lubotcky, I., Lugassy, A. Y., Mizrahi, L. B., Roubinov, T. and Juodzbalys, G. (2025). The Impact of Cigarette Smoking, Waterpipe Smoking, and E-Cigarette Vaping on Peri-Implant Clinical Outcomes and Inflammatory Markers: a Systematic Review and Meta-Analysis. J Oral Maxillofac Res, 4, e1. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41756536


Khodabakhsh Majd, M., Wu, L. Y., Cuadra, G. A. and Brown, A. C. (2026). E-cigarette liquids alter the biogenesis and properties of Aggregatibacter actinomycetemcomitans outer membrane vesicles. Front Cell Infect Microbiol, 1731156. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41743355


Rocha, R. M., Araujo, F. M., Mercadante, F. A., de Souza, A. C., Nogueira, T. E., de Melo, E. S. D., Yamamoto-Silva, F. P. and Silva, B. S. F. (2026). Genotoxicity in oral mucosal cells associated with e-cigarette use: a systematic review and meta-analysis. Oral Surg Oral Med Oral Pathol Oral Radiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41748344


Soysal, F., Oner, F., Guney, Z., Zarinkamar, M. S., Shahsavani, K., Serdar, M. A. and Gokmenoglu, C. (2026). Subclinical Oxidative and Matrix-Regulatory Alterations Associated with Cigarette Smoking and E-Cigarette Use in Periodontally Healthy Adults: A Cross-Sectional Study. J Clin Med, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41682707


Aljoghaiman, E. A., Albrahim, A., Aldarisi, A., Alsafwani, M. and Alhalal, F. (2026). The effect of cigarette and e-cigarette use on periodontal health: A cross-sectional study in Eastern Province, Saudi Arabia. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41551945


Sekar, G., Gundlapalle, P., Elango, S., Surendran, S., Anitha, K., Acchuthakrishnan, K. A. and Nagappan, N. (2025). Vaping Troubles: Exploring the Link Between E-Cigarettes and Oral Lesions in India's Urban Youth. J Pharm Bioallied Sci, Suppl 4, S3410-S3412. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41523055


Strickland-Baker, M. (2026). Disulfiram-like reaction due to the interaction between vaping and metronidazole: a case report. Br Dent J, 2, 89-92. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41577777


Alaee, A., Navabi, N., Razavi, A. and Sharifzadeh, S. S. (2025). Vaping Under the Microscope: Unpacking Iranian Dentists' Insights on Electronic Cigarettes and Their Impact on Oral Health. Addict Health, 1613. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41431634


Barja-Ore, J., Guillen-Calle, B. E., Linan-Bermudez, A., Zagaceta-Guevara, Z., Salazar-Salvatierra, M. E. and Davila, L. T. (2025). Electronic Cigarettes and Oral Health: Bibliometric Mapping of Scientific Evidence. J Contemp Dent Pract, 11, 1109-1114. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41368753


Hmood, A. N., Ebaya, M. M. A. and El-Embaby, A. E. (2025). The in vitro effect of electronic versus conventional cigarettes on color stability and surface roughness of dental resin composites. Sci Rep, 1, 42927. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41326522


Kabli, A. M., Kamal, R. K., Othman, A. A., Almehmadi, F. M., Alrehaili, S. A., Almurowbae, A. S., Alhazmi, R. F., Alrashidi, S. B. and Mirah, M. A. (2025). Oral health effects of tobacco and e-cigarettes in Madinah. Front Oral Health, 1698579. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41394779


Alsenani, M., Alothman, L., Alsenaidi, J., Alnowaiser, A., Aldawsari, M. and Alharbi, N. (2025). Correlation between e-cigarette use and salivary flow rate, pH, and buffering capacity: a cross-sectional pilot study. BMC Oral Health, 1, 1806. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41261418


Li, X., Liu, J., Yang, D., Wang, D., Yue, Q., Zhang, S., Xu, J., Jiang, X., Su, Q., Sun, L., Li, B., Li, K., Su, L. and Zhao, L. (2025). Selected Population-based Oral Health Assessment Following Usage of E-Cigarettes and Combustible Cigarettes. Oral Health Prev Dent, 683-689. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41222216


Perez-Jardon, A., Carvalho, B., Chamorro-Petronacci, C. M., Reboiras-Lopez, M. D., Faria, N. C., Prado, R. F. D., Alves, M. G. O., Silva, F., Padin-Iruegas, M. E., Perez-Sayans, M. and Almeida, J. D. (2025). Impact of Electronic Nicotine Delivery Systems on Oral Mucosa: A Cytopathological and Molecular Study. J Oral Pathol Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41311020


Robson, G., Lim, X. C., Chaudhari, I., Hurley, J., Khalil, S., Amin, V. and Nibali, L. (2025). Trying to clear the air: e-cigarette use and periodontal disease. Br Dent J, 10, 687-692. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41315696


(2025). Vaping and orthodontics: addressing the emerging risks. Br Dent J, 8, 588. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41131317


Bepu, D. A. N., Silva-Sousa, A. C., Lopes-Olhe, F. C., Guedes, D. F. C., Faria, E. S. A. L., Mazzi-Chaves, J. F., Sousa-Neto, M. D. and Souza-Gabriel, A. E. (2025). Experimental in vitro simulation of the impact of e-cigarette vapors on enamel and dentin. Odontology. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41037091


Choueiri, M. E., Laaboudi, F. Z., Zhang, Z., Chmielewski, W. and Rouabhia, M. (2025). Evaluation of the Effect of Electronic Cigarette Aerosol on Normal and Diabetic Human Fibroblast Interaction with Dental Implant Materials. Int J Oral Maxillofac Implants, 0, 1-31. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41171357


Hashimoto, H., Shimazaki, Y., Nonoyama, T., Kito, H., Segawa, N., Okai, M., Uchibori, N., Tomaru, S. and Kawahara, M. (2025). Associations among smoking status, including the use of cigarettes, electronic cigarettes, and heated cigarettes, periodontal condition, and tooth loss in employed Japanese adults: a cross-sectional study. BMC Oral Health, 1, 1590. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41074047


La Rosa, G. R. M., Samaranayake, L. P., Zaura, E., Fuochi, V., Furneri, P. M., Kowalski, J., Chapple, I. and Polosa, R. (2025). Impact of electronic cigarette use on the oral microbiome: a protocol for a systematic review of clinical studies. Syst Rev, 1, 199. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41131626


Yang, I., He, X., Jeon, J., Claussen, H., Arthur, R., Cushenan, P., Weaver, S. R., Luo, R., Black, M., Shannahan, J. and Wright, C. (2025). The impact of vaping behavior on functional changes within the subgingival microbiome. Sci Rep, 1, 34374. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41038906


Aldalaeen, M. O., Haddad, R. H., Alhusamiah, B. K. and Abuejheisheh, A. J. (2025). The Impact of Cigarette Smoking and Vaping Use on the Development and Progression of Periodontitis: A Systematic Review. Health Sci Rep, 9, e71245. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40959186


Chaffee, B. W. (2025). Associations of Current Cigarette, E-Cigarette, and Cannabis Use with Xerostomia. JDR Clin Trans Res, 2.388E+16. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40908802


Sethi, K. K., Srivastava, S., Sinha, A., Mishra, A., Iqbal, H. and Srivastava, T. (2025). Assessment of Salivary Flow Rate and Salivary PH in Subjects with Smoked, Smokeless, and Combined form of Tobacco Habits (Epidemiological-Based Study). Indian J Community Med, Suppl 1, S70-S75. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40949508


La Rosa, G. R. M., Del Giovane, C., Minozzi, S., Kowalski, J., Chapple, I., Amaliya, A., Zakiawati, D., Ludovichetti, F. S., Kim, B. I., Tilakaratne, W. M., Farsalinos, K. and Polosa, R. (2025). Oral adverse event reporting in smoking cessation trials using non-combustible nicotine products: A quality assessment. J Dent, 106057. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40858203


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2