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18.7 Effects of e-cigarette use on smoking
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Relevant news and research: Effects of e-cigarette use on smoking

Auer, R., Tal, K. and Baggio, S. (2025). E-cigarettes for Smoking Cessation: The Courage to Embrace the Science Around Nicotine Addiction. JACC Adv, 9, 102106. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40848529


Feinstein, M. J. P., Erath, T. G., Thrailkill, E. A., DeSarno, M. J., Medina, N., Freitas-Lemos, R., Higgins, S. T. and Klemperer, E. M. (2025). Investigating the substitutability of little cigars/cigarillos, e-cigarettes, and other noncombusted tobacco products for cigarettes using the experimental tobacco marketplace. Exp Clin Psychopharmacol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40920542


Pacek, L. R., Ganz, O., Rubenstein, D., Barnwell, P. V. and McClernon, F. J. (2025). Identifying latent classes of dual cigarette/ENDS users based on motivations for ENDS use: Product substitution versus complementary use. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40910551


Sanchez, L. M., Cho, J., Harlow, A. F., Miech, R. A., Sussman, S., Dai, H. D., Adjei, A., Han, D. H., Li, M., Meza, L., Leventhal, A. M. and Bae, D. (2025). Correlations Between Flavored E-Cigarette Use and Tobacco and Substance Use Among US Youth, 2021 to 2023. Milbank Q. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40961015


Thao Tran, T. P., Pechacek, T. F., Ashley, D. L., Spears, C. A., Kute, N. G. and Weaver, S. R. (2025). Transitions and patterns in concurrent use of cigarettes and electronic cigarettes: An intensive longitudinal study of adults who smoke cigarettes and recently initiated e-cigarette use. Addict Behav, 108474. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40907174


Brouwer, A. F., Shafie-Khorassani, F., Benowitz, N., Shi, N., Baker, T. B., Hayes-Birchler, T. and Piper, M. E. (2025). Urinary tobacco and nicotine exposure biomarkers as predictors of transitions between cigarette and e-cigarette use in the Exhale longitudinal cohort study. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40832891


Chan, G. C. K., Sun, T., Vu, G. and Hall, W. (2025). Caution is needed when interpreting interrupted time series findings on vaping and smoking. Lancet Reg Health West Pac, 101656. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40831736


Cioe, P. A., Lechner, W. V., Stang, G. S., Kahler, C. W., Tashima, K. T., Eissenberg, T. and Tidey, J. W. (2025). Reprint of: The effects of switching to the standardized research electronic cigarette in people with HIV who smoke in the United States. Prev Med, 108389. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40877112


Egger, S., David, M., McCool, J., Hardie, L., Weber, M. F., Luo, Q. and Freeman, B. (2025). Caution is always needed when interpreting population-level vaping and smoking trends-authors' reply. Lancet Reg Health West Pac, 101657. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40822289


Erinoso, O., Kasza, K., Hyland, A. and Pearson, J. (2025). Estimating the likelihood of cigarette maintenance and dual use among people using e-cigarettes for cigarette cessation: Analysis of the Population Assessment of Tobacco and Health Study Waves 5 and 6. Addict Behav, 108458. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40884899


Hartmann-Boyce, J., Begh, R., Conde, M., Shahab, L., Jackson, S. E., Pesko, M. F., Livingstone-Banks, J., Kale, D., Rigotti, N. A., Fanshawe, T., Kneale, D. and Lindson, N. (2025). Response to comment from Egger and McKee entitled 'Unreliable evidence from problematic risk of bias assessments: Comment on Begh et al., 'Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review"'. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40798861


Lisha, N. E., Vora, M., Chaffee, B. W. and Cheng, J. (2025). Identifying and Understanding Use Trajectories of Cigarettes and E-Cigarettes. Subst Use Misuse, 13-Jan. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40750790


Piper, M. E., Kaye, J. T., Piasecki, T. M., Yang, J. J. and Buu, A. (2025). Cannabis use among adults who smoke tobacco: Relations with switching from combusted cigarettes to e-cigarettes or very low nicotine cigarettes. Drug Alcohol Depend, 112821. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40803048


Roulet, S., Kanitscheider, C., Magnani, P. and Kallischnigg, G. (2025). Evaluating Use Patterns of a Closed Electronic Nicotine Delivery System Among Adults in the United States Who Smoke Cigarettes Daily: 8-Week Actual Use Study. JMIR Form Res, e76019. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40854156


Schneider, L. (2025). Study: Vapes Beat Nicotine Replacement Therapy as a Smoking Cessation Tool. JAMA. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40748538


Wang, Y., Cavazos-Rehg, P. A., Cui, Y., Speer, M., LoParco, C. R., McCready, D. M., Yang, Y. T. and Berg, C. J. (2025). The gateway effect of cigarette, e-cigarette, cigar, and alcohol use vs. Cannabis use. Addict Behav, 108451. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40795599


Bonevski, B., Rich, J., Lubman, D. I., Segan, C., Baker, A., Borland, R., Oldmeadow, C., Gartner, C., Walker, N., Dunlop, A., Daglish, M., Bullen, C., Bauld, L., Jacka, D., Garfield, J. B. B., McCrohan, R., Guillaumier, A. and Manning, V. (2025). Nicotine e-cigarettes for smoking cessation following discharge from smoke-free inpatient alcohol and other drug withdrawal services: a pragmatic two-arm, single-blinded, parallel-group, randomised controlled trial. Lancet Public Health, 7, e568-e577. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40602856


Brennan, M. M., Bowe, A. K., Sheridan, A., Doyle, F., Boland, F. and Kavanagh, P. (2025). Evolution of nicotine product use in Ireland 2015-2023, and associations with quit intentions and attempts: an analysis of nationally representative repeated cross-sectional surveys. Lancet Reg Health Eur, 101352. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40678043


Courtney, R. J., Howard, B. C., Barker, D., Petrie, D., Borland, R., Shakeshaft, A., Gartner, C., Mendelsohn, C., Boland, V. C., Henderson, A., Richmond, R. L., Tutka, P., Naughton, F., Hall, W., Zwar, N., Farrell, M., Mattick, R. P. and McRobbie, H. (2025). Vaporized Nicotine Products for Smoking Cessation Among People Experiencing Social Disadvantage : A Randomized Clinical Trial. Ann Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40658956


D'Mello, K., Driezen, P., East, K. A., Fong, G. T. and Hammond, D. (2025). Trends in the use of vaping products and other smoking cessation methods among adults who attempt to stop smoking: Findings from ITC Four Country Smoking and Vaping Surveys (2016-2020). Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40709790


Doherty, E. A., Gregory, K. A., Lu, Y. and Dobbs, P. D. (2025). E-cigarette flavor and device preferences among US pregnant women who smoke: A latent class analysis. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40642760


Egger, S. and McKee, M. (2025). Unreliable evidence from problematic risk of bias assessments: Comment on Begh et al., 'Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review'. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40616471


Egger, S. J., David, M., Weber, M. F., Luo, Q., Dessaix, A. and Freeman, B. (2025). Trends in adolescent smoking prevalence before and after the emergence of vaping in Australia: an interrupted time series analysis, 1999-2023. Med J Aust. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40714936


Ford, A., McMillan, L., Soar, K., Pesola, F., Notley, C., Brown, R., Ward, E., Gardner, B., Varley, A., Mair, C., Lennon, J., Brierley, J., Edwards, A., Mitchell, D., Robson, D., Hajek, P., Tyler, A., Parrott, S., Li, J., Bauld, L. and Cox, S. (2025). Exploring how an e-cigarette intervention influenced tobacco smoking behaviour in people accessing homelessness services: Findings from the SCeTCH trial process evaluation. Int J Drug Policy, 104901. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40616874


Halvorson, M. A., Epstein, M., Karryn Satchell, A., Paulette, A., Oesterle, S. and Kuklinski, M. R. (2025). Links between young adults' reasons for trying electronic nicotine delivery systems (ENDS), smoking history, and prospective cigarette and ENDS use. Addict Behav, 108420. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40664019


Jones, A. A., Robison, J. H., Smit, T., Brett, E., Zvolensky, M. J. and Garey, L. (2025). Nicotine dependence, perceived barriers, and affective vulnerability among individuals engaging in dual use who report relapse: Implications for targeted treatment. Addict Behav, 108422. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40652807


Klemperer, E. M., DeSarno, M. J., Tidey, J. W., Gaalema, D. E., Nolder, K. A., Feinstein, M. J. P., Wiley, R. C. and Higgins, S. T. (2025). E-cigarette use frequency mediates effects in three randomized controlled trials of reduced nicotine cigarettes with tobacco vs preferred flavor E-cigarettes in high-risk populations in the U.S. Prev Med, 108353. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40628358


Mongilio, J. M., Staff, J., Seto, C. H., Maggs, J. L. and Evans-Polce, R. J. (2025). Risk of adolescent cigarette use in three UK birth cohorts before and after e-cigarettes. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40730479


Razali, M. F., Riyadzi, M. R., Abd Hamid, H. A., Wan-Fei, K. and Yusoff, U. N. (2025). Prevalence of adolescent dual tobacco use and its associated factors: findings from a cross-sectional study. BMJ Open, 7, e097974. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40713049


Comiford, A. L., Rhoades, D. A., Dvorak, J. D., Ding, K., Collins, N., Blair, A. L. and Doescher, M. P. (2025). E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis. AJPM Focus, 2, 100302. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40458594


Filion, K. B., Zolotarova, T., Hebert-Losier, A., Windle, S. B., Reynier, P., Greenspoon, T., Brandys, T., Fulop, T., Nguyen, T., Elkouri, S., Wilderman, I., Bertrand, O. F., Bostwick, J. A., Lacasse, Y., Pakhale, S. and Eisenberg, M. J. (2025). The Effect of 12-Week e-Cigarette Use on Smoking Abstinence at 1 Year: The E3 Trial. JACC Adv, 6 Pt 2, 101833. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40579065


Jackson, S. E. (2025). Dual Use of e-cigarettes alongside cigarettes encompasses varied behavior patterns and motives that have different implications for health and smoking cessation. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40474553


Kumar, S., Gawde, N. and Mini, G. K. (2025). Tobacco cessation among dual users: analysis of two rounds of Global Adult Tobacco Survey, India. J Public Health (Oxf). Available from: https://www.ncbi.nlm.nih.gov/pubmed/40519204


Andrayas, A., Heron, J., Khouja, J., Jones, H., Munafo, M., Sallis, H., Hines, L. and Curnow, E. (2025). The association of modifiable and socio-demographic factors with first transitions from smoking to exclusive e-cigarette use, dual use or no nicotine use: Findings from the Avon Longitudinal Study of Parents and Children United Kingdom birth cohort. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40364509


Carpenter, M. J. and Klemperer, E. M. (2025). Seeing the forest for the trees: a commentary on 'real-world' e-cigarette use and readiness to stop smoking among adults who smoke. Am J Drug Alcohol Abuse, 1-Mar. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40311063


Cioe, P. A., Lechner, W. V., Stang, G. S., Kahler, C. W., Tashima, K. T., Eissenberg, T. and Tidey, J. W. (2025). The effects of switching to the standardized research electronic cigarette in people with HIV who smoke in the United States. Prev Med, 108309. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40379032


Egger, S., David, M., Weber, M., Luo, Q. and Freeman, B. (2025). Misread signals: a misinterpretation of population-level vaping and smoking trends. Public Health Res Pract. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40443071


Falarowski, C., Pieper, E., Rabenstein, A., Mallock-Ohnesorg, N., Burgmann, N., Franzen, K., Gertzen, M., Koller, G., Nowak, D., Rahofer, A., Rieder, B., de Oliveira Pinto Kise, G. R., Schulz, T., Strohmeyer, E., Laux, P., Luch, A. and Ruther, T. (2025). Disposable e-cigarettes and their nicotine delivery, usage pattern, and subjective effects in occasionally smoking adults. Sci Rep, 1, 16270. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40346191


Hamoud, J., Hanewinkel, R., Andreas, S., Ammous, O., Saalfrank, M., Sussman, S., Unger, J. B., Pisinger, C. and Mathes, T. (2025). A systematic review investigating the impact of dual use of e-cigarettes and conventional cigarettes on smoking cessation. ERJ Open Res, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40337339


Klemperer, E. M., Feinstein, M. J. P., Marsh, K., Villanti, A. C., Carpenter, M. J., Skelly, J. M., DeSarno, M. J. and Higgins, S. T. (2025). A factorial randomized clinical trial of nicotine replacement therapy and treatment recommendations to quit vs continue e-cigarettes when quitting smoking in young adult dual users. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40448340


Rojas, S. V., Kyanko, K. A., Wisniewski, R., O'Connor, K., Li, R., Xiang, G., Vojjala, M., Wilker, O., Sherman, S. E. and Stevens, E. R. (2025). Patient perceptions of the use of e-cigarettes in smoking treatment programs: a qualitative analysis. Addict Sci Clin Pract, 1, 45. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40442834


Selya, A., Kim, S., Shiffman, S. and Goldenson, N. (2025). Repeated point-prevalence of switching away from smoking after electronic nicotine delivery systems (ENDS) purchase. Harm Reduct J, 1, 71. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40316985


Selya, A., Niaura, R. and Kim, S. (2025). Clustering of risk behaviors and classification performance in modeling adolescent risk: The example of the association between E-cigarette use and cigarette smoking. Drug Alcohol Depend, 112716. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40435593


Anderer, S. (2025). Rise in Vaping Keeps Tobacco Use High. JAMA. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40215077


Edwards, K. C., Garcia-Rosales, K., Goniewicz, M., Ashley, D., Hatsukami, D., Wang, L., Feng, J., Blount, B. C., Sharma, E., Merrill, L. S., Taylor, K., Duffy, K., Harvanko, A., Del Valle-Pinero, A., Christensen, C. H., Chang, C. M., van Bemmel, D., Rivers, D. L., Mishina, E. V., Tolliver, E. A., Roh, E. J., Hammad, H. T., Kc, P., Xu, K., Montes de Oca, R., Cheng, Y. C., Everard, C., Kimmel, H. L., Blanco, C., Compton, W. and Hyland, A. (2025). ENDS use and nicotine exposure among adults who use ENDS alone or with cigarettes: The PATH Study 2013-2019. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40253576


Egger, S., David, M., McCool, J., Hardie, L., Weber, M. F., Luo, Q. and Freeman, B. (2025). Trends in smoking prevalence among 14-15-year-old adolescents before and after the emergence of vaping in New Zealand; an interrupted time series analysis of repeated cross-sectional data, 1999-2023. Lancet Reg Health West Pac, 101522. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40226779


Halliday, D. M., Song, A. V. and Nguyen, N. (2025). E-cigarette and cannabis use among current and recently quit smokers: Co-use and Co-cessation. Addict Behav Rep, 100611. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40290632


Hughes, J., Hughes, K., Sykes, G., O'Reilly, M., Sutton, C., Goodwin, J. and Karim, K. (2025). What Is the Role of Imagined Futures in the Development of E-Cigarette Use among Young People?. Sociology, 2, 231-249. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40226107


La Rosa, G. R. M., Polosa, R. and O'Leary, R. (2025). Effect of E-Cigarette Substitution for Cigarettes on Weight Status: A Systematic Review. Arch Med Res, 5, 103211. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40174301


Micha, J. P., Rettenmaier, M. A., Bohart, R. D. and Goldstein, B. H. (2025). Vaping and Smoking Cessation. Subst Use Misuse, 1-Apr. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40200569


Ameral, V., Sofuoglu, M. and Kelly, M. M. (2025). Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective. Expert Rev Clin Pharmacol, 4, 189-196. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40047379


Banjo, E., Ahadian, Z., Kasaraneni, N., Chang, H., Perera, S., Emory, K. and Crotty Alexander, L. E. (2025). Factors driving switching from vaping of e-cigarettes to smoking tobacco and initiation of multi-inhalant use. medRxiv. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40093245


Carpenter, M. J., Smith, T. T., Walters, K. J., Wahlquist, A. E., Koval, K. R. and Klemperer, E. M. (2025). Evaluation of Dual Use: Real Time Reductions in Combustible Cigarette Smoking During Co-Occurring Use of E-Cigarettes A Secondary Analysis of a Naturalistic Randomized Clinical Trial. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40037836


Conde, M., Pesko, M. F., Shahab, L., Begh, R., Lindson, N., Jackson, S. E., Kale, D., Kneale, D., Livingstone-Banks, J. and Hartmann-Boyce, J. (2025). Recommendations for future research exploring e-cigarette use and later cigarette smoking in young people: Results from a consultation exercise. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40041956


Dai, H. D., Qiu, F., Dai, R. and Cheng, X. (2025). Machine Learning of Smoking Relapse: the Role of Racial Differences and E-Cigarette Vaping Characteristics on Former Smokers. J Racial Ethn Health Disparities. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40117048


Egger, S., Freeman, B., McCool, J. and Hardie, L. (2025). The tobacco lobby claims vaping is displacing youth smoking – a close look at the evidence tells another story. The Conversation. Available from: https://theconversation.com/the-tobacco-lobby-claims-vaping-is-displacing-youth-smoking-a-close-look-at-the-evidence-tells-another-story-252283


Goldenson, N. I., Shiffman, S., Sembower, M. A., Selya, A., Pype, S. and Black, R. A. (2025). Evaluating the Effect of the JUUL2 System With 5 Flavors on Cigarette Smoking and Tobacco Product Use Behaviors Among Adults Who Smoke Cigarettes: 6-Week Actual Use Study. Interact J Med Res, e60620. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40138686


Hoeppner, B. B., Eddie, D., Schick, M., Hoeppner, S. S., Kelly, L. and Kelly, J. F. (2024). Feasibility of and reactivity to ecological momentary assessment (EMA) during electronic cigarette use initiation in adults who smoke daily. Eur J Psychiatry, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40124422


Hunter, I. and Frasca, D. J. (2025). Nicotine Electronic Cigarettes for Smoking Cessation. Am Fam Physician, 3, 210-211. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40106284


Ji, W., Shi, L., Lin, X., Ji, Z., Zhao, Z., Chen, Y., Huang, P., Wang, X., Dai, X., Cheng, J., Guo, L., Wu, D., Chen, Y., Wu, Z. and Chen, X. (2025). Gender differences in preferences, gateway effects, and potential motivations among e-cigarette users in China. Front Public Health, 1417218. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40078752


Joseph, M., Morean, M. E., Wu, R., Krishnan-Sarin, S., O'Malley, S. S. and Bold, K. W. (2025). Examining E-Cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration Among US Adults Using E-Cigarettes in a Smoking Cessation Attempt. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40056399


Morgan, T., He, M., Nicholson, A., El Shahawy, O., Sherman, S. E. and Stevens, E. R. (2025). Using Text Messaging Ecological Momentary Assessment to Record Changes in e-Cigarette and Combustible Cigarette Use: Pilot Randomized Clinical Trial. JMIR Form Res, e66709. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40116747


Nip, J., Zhang, J., Stanley, J., Waa, A., Ball, J., Tautolo, E. S., Agar, T. K., Quah, A. C., Fong, G. T. and Edwards, R. (2025). Patterns and experiences of smoking, electronic cigarettes (vapes) and heated tobacco use among people who smoke or who recently quit. N Z Med J, 1612, 21-46. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40146955


Quach, N. E., Pierce, J. P., Chen, J., Dang, B., Stone, M. D., Strong, D. R., Trinidad, D. R., McMenamin, S. B. and Messer, K. (2025). Daily or Nondaily Vaping and Smoking Cessation Among Smokers. JAMA Netw Open, 3, e250089. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40042845


Schiek, H., Esch, T. and Hoetger, C. (2025). Initial assessment of a novel smoking cessation program integrating app-based behavioral therapy and an electronic cigarette: results of a pilot study. Addict Sci Clin Pract, 1, 31. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40140969


Baggio, S., Bruggmann, P., Schoeni, A., Abolhassani, N., Tal, K., Pohle, S., Frei, A., Humair, J. P., Jacot-Sadowski, I., Vetsch, J., Lehner, L., Rihs, A., Getaz, L., Berthet, A., Haller, M., Stuber, M., Jakob, J. and Auer, R. (2025). Efficacy of e-cigarettes for smoking cessation in populations with psychiatric and/or substance use problems: A secondary analysis of a randomized controlled trial. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39902147


Danzo, S., Epstein, M., Kosterman, R., Halvorson, M. A., Caouette, J. D., Satchell, K., Kuklinski, M. R. and Oesterle, S. (2025). Does cannabis and electronic nicotine delivery system (ENDS) use interfere with cigarette smoking cessation in young adulthood?. Addict Behav, 108289. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39938143


East, K., Taylor, E., McNeill, A., Bakolis, I., Taylor, A. E., Maynard, O. M., Munafo, M. R. and Khouja, J. (2025). Perceived Harm of Vaping Relative to Smoking and Associations With Subsequent Smoking and Vaping Behaviors Among Young Adults: Evidence From a UK Cohort Study. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39947229


Evans-Polce, R. J., Mongilio, J. M., Kcomt, L., Chen, B. and McCabe, S. E. (2025). Trends and Sociodemographic Differences in Tobacco/Nicotine Transitions Among U.S. Adolescents and Young Adults Using e-cigarettes, 2014-2023. J Adolesc Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39969469


Miech, R., Leventhal, A., Patrick, M. and Rodriguez, N. (2025). Trends in use of cigarettes and e-cigarettes among young adults who had smoked in adolescence: 2017-2022. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39890453


Piasecki, T. M., Slutske, W. S., Bolt, D. M., Jorenby, D. E. and Piper, M. E. (2025). Effects of very low nicotine cigarettes, e-cigarettes, and nicotine patches on daily own-cigarette abstinence in a randomized controlled switching trial. Drug Alcohol Depend, 112576. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39914192


Qadir, N., Palacio, C. and Fuest, S. (2025). EBM BLS: E-Cigarettes and Varenicline are Both Effective for Smoking Cessation. J Gen Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40016379


Shaughnessy, A. F. (2025). e-Cigarettes (Vaping) Can Help People Quit Smoking, Although the Effect May Decrease Over Time. Am Fam Physician, 2, 181-182. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39964935


Shiffman, S., Kim, S., Goldenson, N. I. and Sembower, M. A. (2025). Readiness to stop smoking and subsequent switching away to electronic nicotine delivery systems among adults who smoke cigarettes. Am J Drug Alcohol Abuse, 1-Nov. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39977664


Begh, R., Conde, M., Fanshawe, T. R., Kneale, D., Shahab, L., Zhu, S., Pesko, M., Livingstone-Banks, J., Lindson, N., Rigotti, N. A., Tudor, K., Kale, D., Jackson, S. E., Rees, K. and Hartmann-Boyce, J. (2025). Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39888213


Cole, E., Segan, C., Filia, S., Kyi, J. and Baird, D. (2024). Therapeutic vapes for smoking cessation and nicotine dependence. Aust Prescr, 6, 171-176. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39777042


Foxon, F. and Niaura, R. (2025). Use of nicotine products, prescription drug products, and other methods to stop smoking by US adults in the 2022 National Health Interview Survey. Intern Emerg Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39760947


Gravely, S., Sweanor, D., Driezen, P., Levy, D. T., Fong, G. T., Quah, A. C. K., Craig, L. V., Chung-Hall, J., Kaai, S. C. and Cummings, K. M. (2025). Use of nicotine vaping products during an attempt to quit smoking by Canadian adults who smoke or recently quit: findings from the 2022 Canada International Tobacco Control Four Country Smoking and Vaping Survey. Health Promot Chronic Dis Prev Can, 1, 54-60. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39817711


Hartmann-Boyce, J., Chan, J., Zhitnik, E., Pesola, F., Hajek, P. and Lindson, N. (2025). Longitudinal patterns in smoking abstinence in trials of e-cigarettes for smoking cessation: secondary analysis of data from a systematic review, with meta-analyses. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39756408


Jackson, S. E., Brown, J., Buss, V. and Shahab, L. (2025). Prevalence of Popular Smoking Cessation Aids in England and Associations With Quit Success. JAMA Netw Open, 1, e2454962. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39821398


Jackson, S. E., Cox, S., Shahab, L. and Brown, J. (2025). Trends and patterns of dual use of combustible tobacco and e-cigarettes among adults in England: A population study, 2016-2024. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39842468


Kale, D., Beard, E., Marshall, A. M., Pervin, J., Wu, Q., Ratschen, E. and Shahab, L. (2025). Providing an e-cigarette starter kit for smoking cessation and reduction as adjunct to usual care to smokers with a mental health condition: findings from the ESCAPE feasibility study. BMC Psychiatry, 1, 13. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39754165


Kaplan, B., Tseng, T. Y., Hardesty, J. J., Czaplicki, L. and Cohen, J. E. (2025). Beneficial and Harmful Tobacco Use Transitions Associated with ENDS in the US. Am J Prev Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39880060


Lindson, N., Butler, A. R., McRobbie, H., Bullen, C., Hajek, P., Wu, A. D., Begh, R., Theodoulou, A., Notley, C., Rigotti, N. A., Turner, T., Livingstone-Banks, J., Morris, T. and Hartmann-Boyce, J. (2025). Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev, 1, CD010216. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39878158


Mosimann, A. F., Guttinger, E. M., Tal, K., Schoeni, A., Baggio, S., Sambiagio, N., Berthet, A., Jacot-Sadowski, I., Humair, J. P., Brutsche, M., Frei, A., Haller, M. L., Auer, R. and Jakob, J. (2025). E-liquid flavors and nicotine concentration choices over 6 months after a smoking cessation attempt with ENDS: Secondary analyses of a randomized controlled trial. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39816168


Sifat, M. S., Alexander, A. C., Businelle, M. S., Frank-Pearce, S. G., Boozary, L. K., Wagener, T. L., Ahluwalia, J. S. and Kendzor, D. E. (2024). E-Cigarette switching and financial incentives to promote combustible cigarette cessation among adults accessing shelter services: A pilot study. Drug Alcohol Depend Rep, 100295. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39764385


Smith, T. T., Wahlquist, A. E., Wagener, T. L., Cummings, K. M. and Carpenter, M. J. (2024). The impact of non-tobacco e-cigarette flavoring on e-cigarette uptake, cigarette smoking reduction, and cessation: A secondary analysis of a nationwide clinical trial. Addict Behav, 108240. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39787830


Derissen, M., Scheliga, S., Clemens, B., Leiding, D., Kroger, K., Bohner, H. and Habel, U. (2024). Smoking cessation and harm reduction: a systematic overview of ongoing, randomized controlled trials. BMC Psychiatry, 1, 897. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39690417


Lindson, N., Livingstone-Banks, J., Butler, A. R., Levy, D. T., Barnett, P., Theodoulou, A., Notley, C., Rigotti, N. A., Chen, Y. and Hartmann-Boyce, J. (2024). An update of a systematic review and meta-analyses exploring flavours in intervention studies of e-cigarettes for smoking cessation. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39702981


O'Leary, R., La Rosa, G. R. M. and Polosa, R. (2025). Examining e-cigarettes as a smoking cessation treatment: A critical umbrella review analysis. Drug Alcohol Depend, 112520. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39662357


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2