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18.7 Effects of e-cigarette use on smoking
Foreword

Relevant news and research: Effects of e-cigarette use on smoking

Ameral, V., Sofuoglu, M. and Kelly, M. M. (2025). Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective. Expert Rev Clin Pharmacol, 4, 189-196. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40047379


Banjo, E., Ahadian, Z., Kasaraneni, N., Chang, H., Perera, S., Emory, K. and Crotty Alexander, L. E. (2025). Factors driving switching from vaping of e-cigarettes to smoking tobacco and initiation of multi-inhalant use. medRxiv. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40093245


Carpenter, M. J., Smith, T. T., Walters, K. J., Wahlquist, A. E., Koval, K. R. and Klemperer, E. M. (2025). Evaluation of Dual Use: Real Time Reductions in Combustible Cigarette Smoking During Co-Occurring Use of E-Cigarettes A Secondary Analysis of a Naturalistic Randomized Clinical Trial. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40037836


Conde, M., Pesko, M. F., Shahab, L., Begh, R., Lindson, N., Jackson, S. E., Kale, D., Kneale, D., Livingstone-Banks, J. and Hartmann-Boyce, J. (2025). Recommendations for future research exploring e-cigarette use and later cigarette smoking in young people: Results from a consultation exercise. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40041956


Dai, H. D., Qiu, F., Dai, R. and Cheng, X. (2025). Machine Learning of Smoking Relapse: the Role of Racial Differences and E-Cigarette Vaping Characteristics on Former Smokers. J Racial Ethn Health Disparities. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40117048


Egger, S., Freeman, B., McCool, J. and Hardie, L. (2025). The tobacco lobby claims vaping is displacing youth smoking – a close look at the evidence tells another story. The Conversation. Available from: https://theconversation.com/the-tobacco-lobby-claims-vaping-is-displacing-youth-smoking-a-close-look-at-the-evidence-tells-another-story-252283


Goldenson, N. I., Shiffman, S., Sembower, M. A., Selya, A., Pype, S. and Black, R. A. (2025). Evaluating the Effect of the JUUL2 System With 5 Flavors on Cigarette Smoking and Tobacco Product Use Behaviors Among Adults Who Smoke Cigarettes: 6-Week Actual Use Study. Interact J Med Res, e60620. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40138686


Hoeppner, B. B., Eddie, D., Schick, M., Hoeppner, S. S., Kelly, L. and Kelly, J. F. (2024). Feasibility of and reactivity to ecological momentary assessment (EMA) during electronic cigarette use initiation in adults who smoke daily. Eur J Psychiatry, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40124422


Hunter, I. and Frasca, D. J. (2025). Nicotine Electronic Cigarettes for Smoking Cessation. Am Fam Physician, 3, 210-211. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40106284


Ji, W., Shi, L., Lin, X., Ji, Z., Zhao, Z., Chen, Y., Huang, P., Wang, X., Dai, X., Cheng, J., Guo, L., Wu, D., Chen, Y., Wu, Z. and Chen, X. (2025). Gender differences in preferences, gateway effects, and potential motivations among e-cigarette users in China. Front Public Health, 1417218. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40078752


Joseph, M., Morean, M. E., Wu, R., Krishnan-Sarin, S., O'Malley, S. S. and Bold, K. W. (2025). Examining E-Cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration Among US Adults Using E-Cigarettes in a Smoking Cessation Attempt. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40056399


Morgan, T., He, M., Nicholson, A., El Shahawy, O., Sherman, S. E. and Stevens, E. R. (2025). Using Text Messaging Ecological Momentary Assessment to Record Changes in e-Cigarette and Combustible Cigarette Use: Pilot Randomized Clinical Trial. JMIR Form Res, e66709. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40116747


Nip, J., Zhang, J., Stanley, J., Waa, A., Ball, J., Tautolo, E. S., Agar, T. K., Quah, A. C., Fong, G. T. and Edwards, R. (2025). Patterns and experiences of smoking, electronic cigarettes (vapes) and heated tobacco use among people who smoke or who recently quit. N Z Med J, 1612, 21-46. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40146955


Quach, N. E., Pierce, J. P., Chen, J., Dang, B., Stone, M. D., Strong, D. R., Trinidad, D. R., McMenamin, S. B. and Messer, K. (2025). Daily or Nondaily Vaping and Smoking Cessation Among Smokers. JAMA Netw Open, 3, e250089. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40042845


Schiek, H., Esch, T. and Hoetger, C. (2025). Initial assessment of a novel smoking cessation program integrating app-based behavioral therapy and an electronic cigarette: results of a pilot study. Addict Sci Clin Pract, 1, 31. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40140969


Baggio, S., Bruggmann, P., Schoeni, A., Abolhassani, N., Tal, K., Pohle, S., Frei, A., Humair, J. P., Jacot-Sadowski, I., Vetsch, J., Lehner, L., Rihs, A., Getaz, L., Berthet, A., Haller, M., Stuber, M., Jakob, J. and Auer, R. (2025). Efficacy of e-cigarettes for smoking cessation in populations with psychiatric and/or substance use problems: A secondary analysis of a randomized controlled trial. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39902147


Danzo, S., Epstein, M., Kosterman, R., Halvorson, M. A., Caouette, J. D., Satchell, K., Kuklinski, M. R. and Oesterle, S. (2025). Does cannabis and electronic nicotine delivery system (ENDS) use interfere with cigarette smoking cessation in young adulthood?. Addict Behav, 108289. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39938143


East, K., Taylor, E., McNeill, A., Bakolis, I., Taylor, A. E., Maynard, O. M., Munafo, M. R. and Khouja, J. (2025). Perceived Harm of Vaping Relative to Smoking and Associations With Subsequent Smoking and Vaping Behaviors Among Young Adults: Evidence From a UK Cohort Study. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39947229


Evans-Polce, R. J., Mongilio, J. M., Kcomt, L., Chen, B. and McCabe, S. E. (2025). Trends and Sociodemographic Differences in Tobacco/Nicotine Transitions Among U.S. Adolescents and Young Adults Using e-cigarettes, 2014-2023. J Adolesc Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39969469


Miech, R., Leventhal, A., Patrick, M. and Rodriguez, N. (2025). Trends in use of cigarettes and e-cigarettes among young adults who had smoked in adolescence: 2017-2022. Tob Control. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39890453


Piasecki, T. M., Slutske, W. S., Bolt, D. M., Jorenby, D. E. and Piper, M. E. (2025). Effects of very low nicotine cigarettes, e-cigarettes, and nicotine patches on daily own-cigarette abstinence in a randomized controlled switching trial. Drug Alcohol Depend, 112576. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39914192


Qadir, N., Palacio, C. and Fuest, S. (2025). EBM BLS: E-Cigarettes and Varenicline are Both Effective for Smoking Cessation. J Gen Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40016379


Shaughnessy, A. F. (2025). e-Cigarettes (Vaping) Can Help People Quit Smoking, Although the Effect May Decrease Over Time. Am Fam Physician, 2, 181-182. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39964935


Shiffman, S., Kim, S., Goldenson, N. I. and Sembower, M. A. (2025). Readiness to stop smoking and subsequent switching away to electronic nicotine delivery systems among adults who smoke cigarettes. Am J Drug Alcohol Abuse, 1-Nov. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39977664


Begh, R., Conde, M., Fanshawe, T. R., Kneale, D., Shahab, L., Zhu, S., Pesko, M., Livingstone-Banks, J., Lindson, N., Rigotti, N. A., Tudor, K., Kale, D., Jackson, S. E., Rees, K. and Hartmann-Boyce, J. (2025). Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39888213


Cole, E., Segan, C., Filia, S., Kyi, J. and Baird, D. (2024). Therapeutic vapes for smoking cessation and nicotine dependence. Aust Prescr, 6, 171-176. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39777042


Foxon, F. and Niaura, R. (2025). Use of nicotine products, prescription drug products, and other methods to stop smoking by US adults in the 2022 National Health Interview Survey. Intern Emerg Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39760947


Gravely, S., Sweanor, D., Driezen, P., Levy, D. T., Fong, G. T., Quah, A. C. K., Craig, L. V., Chung-Hall, J., Kaai, S. C. and Cummings, K. M. (2025). Use of nicotine vaping products during an attempt to quit smoking by Canadian adults who smoke or recently quit: findings from the 2022 Canada International Tobacco Control Four Country Smoking and Vaping Survey. Health Promot Chronic Dis Prev Can, 1, 54-60. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39817711


Hartmann-Boyce, J., Chan, J., Zhitnik, E., Pesola, F., Hajek, P. and Lindson, N. (2025). Longitudinal patterns in smoking abstinence in trials of e-cigarettes for smoking cessation: secondary analysis of data from a systematic review, with meta-analyses. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39756408


Jackson, S. E., Brown, J., Buss, V. and Shahab, L. (2025). Prevalence of Popular Smoking Cessation Aids in England and Associations With Quit Success. JAMA Netw Open, 1, e2454962. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39821398


Jackson, S. E., Cox, S., Shahab, L. and Brown, J. (2025). Trends and patterns of dual use of combustible tobacco and e-cigarettes among adults in England: A population study, 2016-2024. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39842468


Kale, D., Beard, E., Marshall, A. M., Pervin, J., Wu, Q., Ratschen, E. and Shahab, L. (2025). Providing an e-cigarette starter kit for smoking cessation and reduction as adjunct to usual care to smokers with a mental health condition: findings from the ESCAPE feasibility study. BMC Psychiatry, 1, 13. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39754165


Kaplan, B., Tseng, T. Y., Hardesty, J. J., Czaplicki, L. and Cohen, J. E. (2025). Beneficial and Harmful Tobacco Use Transitions Associated with ENDS in the US. Am J Prev Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39880060


Lindson, N., Butler, A. R., McRobbie, H., Bullen, C., Hajek, P., Wu, A. D., Begh, R., Theodoulou, A., Notley, C., Rigotti, N. A., Turner, T., Livingstone-Banks, J., Morris, T. and Hartmann-Boyce, J. (2025). Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev, 1, CD010216. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39878158


Mosimann, A. F., Guttinger, E. M., Tal, K., Schoeni, A., Baggio, S., Sambiagio, N., Berthet, A., Jacot-Sadowski, I., Humair, J. P., Brutsche, M., Frei, A., Haller, M. L., Auer, R. and Jakob, J. (2025). E-liquid flavors and nicotine concentration choices over 6 months after a smoking cessation attempt with ENDS: Secondary analyses of a randomized controlled trial. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39816168


Sifat, M. S., Alexander, A. C., Businelle, M. S., Frank-Pearce, S. G., Boozary, L. K., Wagener, T. L., Ahluwalia, J. S. and Kendzor, D. E. (2024). E-Cigarette switching and financial incentives to promote combustible cigarette cessation among adults accessing shelter services: A pilot study. Drug Alcohol Depend Rep, 100295. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39764385


Smith, T. T., Wahlquist, A. E., Wagener, T. L., Cummings, K. M. and Carpenter, M. J. (2024). The impact of non-tobacco e-cigarette flavoring on e-cigarette uptake, cigarette smoking reduction, and cessation: A secondary analysis of a nationwide clinical trial. Addict Behav, 108240. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39787830


Derissen, M., Scheliga, S., Clemens, B., Leiding, D., Kroger, K., Bohner, H. and Habel, U. (2024). Smoking cessation and harm reduction: a systematic overview of ongoing, randomized controlled trials. BMC Psychiatry, 1, 897. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39690417


Lindson, N., Livingstone-Banks, J., Butler, A. R., Levy, D. T., Barnett, P., Theodoulou, A., Notley, C., Rigotti, N. A., Chen, Y. and Hartmann-Boyce, J. (2024). An update of a systematic review and meta-analyses exploring flavours in intervention studies of e-cigarettes for smoking cessation. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39702981


O'Leary, R., La Rosa, G. R. M. and Polosa, R. (2025). Examining e-cigarettes as a smoking cessation treatment: A critical umbrella review analysis. Drug Alcohol Depend, 112520. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39662357


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2