Home
3.10 Eye diseases
Foreword

Relevant news and research: Eye diseases

Asadollahi Shahir, A. A., Khoshakhlagh, A. H., Mehrzad, F., Ghaderi, A., Gruszecka-Kosowska, A., Ghorbani, S., Haerifar, F. and Hashemian Esfahani, S. S. (2025). Serum heavy metal levels from tobacco smoke and Buerger's disease. Sci Rep, 1, 40821. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41258278


Bener, A., Erdogan, A., Oria, L., Karim, H. and Hanoglu, L. (2025). The role risk of cigarette smoking, alcohol consumption, sleeping disorder, and mental health with hearing loss among stroke patients. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41190052


Han, B., Tong, X., Raynald, Jia, B., Mo, D., Gao, F., Ma, N., Sun, X. and Miao, Z. (2025). Impact of smoking status and smoking index on outcomes in patients with acute basilar artery occlusion. Front Neurol, 1623245. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41245862


Loffredo, L., Maggio, E., Bartimoccia, S., Magna, A., Tote, C. M., Bagnato, C., Cinicola, B. L., Armeli, F., Leonardo, A., D'Amico, A., Greco, E., Frati, G., Biondi-Zoccai, G., Spalice, A., Angeloni, A., Pignatelli, P., Violi, F., Zicari, A. M., Carnevale, R. and Smoking Prevention Study, G. (2025). Tobacco Smoke Exposure and Oxidative Stress: The Role of Circulating Lipopolysaccharides in Heated and Conventional Products. Antioxidants (Basel), 11. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41300474


Tahsin Ozpolat, H., Sanal, B., Khatiwada, N. and Thajudeen, B. (2025). Aortic dissection: Presentation of fibromuscular disease in elderly smokers. Am J Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41177427


Tasdighi, E., Yao, Z., Dardari, Z. A., Jha, K. K., Osuji, N., Rajan, T., Boakye, E., Matsushita, K., Simonsick, E. M., Lima, J. A. C., Lloyd-Jones, D. M., Cohen, D. L., Appel, L. J., Khera, A., Hall, M. E., Rodriguez, C. J., Judd, S., Cole, S. A., Ramachandran, V. S., Benjamin, E. J., Lotufo, P. A., Bittencourt, M. S., El Khoudary, S. R., Thurston, R. C., Derby, C. A., Psaty, B. M., Eaton, C. B., LaMonte, M. J., Cawthon, P. M., Orwoll, E. S., Bhatnagar, A., DeFilippis, A. P. and Blaha, M. J. (2025). Association between cigarette smoking status, intensity, and cessation duration with long-term incidence of nine cardiovascular and mortality outcomes: The Cross-Cohort Collaboration (CCC). PLoS Med, 11, e1004561. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41252354


Youssef, N., Abdellatif, M., Omar, A., Abdel Mageed, M., Essmat, A., Abdul Mawla, N., Ahmed, H., Assem, A., Abualkasem, T., Darwish, A., Abd ElRazek, H., Arfa, M., Beshir, A., Youssef, I., Gouda, N., Salem, R., Safwat, O., Elmahdy, H., Hassan, M., Ahmed, F., Metwally, A., Abdelrahman, M., Gerges, M., Ali, A. R., Roushdy, A., Ahmed, W. and Abdelmoniem, S. (2025). Impact of Dyslipidemia, Cardiovascular Disease, Smoking, and Stroke Type by Brain Imaging on Pneumonia Risk in ICU Stroke Patients: A Cross-Sectional Observational Study. Clin Ter, 6, 810-817. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41267601


Zhou, J., Hou, X., Zheng, Z., Quan, T., Meng, X., Xu, Y., Zhao, L., Ren, X., Yang, L., Shi, Y. and Qin, X. (2025). Chronic nicotine exposure drives dose-dependent pulmonary hypertension and cardiopulmonary remodeling: Preclinical and clinical validation. Microvasc Res, 104884. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41242379


Zhu, Y., Kilian, C., Lemp, J., Llamosas-Falcon, L. and Probst, C. (2025). Additive interactions of smoking with obesity on ischemic heart disease mortality: a national prospective cohort study in the United States. Int J Epidemiol, 6. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41208171


Australian Institute of Health and Welfare (2025). Heart, stroke and vascular disease: Australian facts. . Available from: https://www.aihw.gov.au/reports/heart-stroke-vascular-diseases/hsvd-facts


Cieri, I. F., Rodriguez Alvarez, A. A., Boya, M. N., Patel, S., Nurko, A., Teeple, W. and Dua, A. (2025). Association Between Smoking and Thromboelastography With Platelet Mapping Parameters in Peripheral Artery Disease Patients. J Surg Res, 647-658. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41125059


de Ruiter, S. C., Tschiderer, L., Grobbee, D. E., Rockenschaub, P., Ruigrok, Y. M., Willeit, P., den Ruijter, H. M., Schmidt, A. F. and Peters, S. A. E. (2025). Smoking as a Risk Factor for Cardiovascular Disease in Females and Males: Observational and Mendelian Randomisation Analyses in the UK Biobank. Glob Heart, 1, 93. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41111900


Gao, S., Huang, S., Liu, X., Yu, M. and Zhao, L. (2025). Impact of smoking cessation on cardiovascular outcomes in patients with myocardial infarction with nonobstructive coronary arteries. Am J Prev Cardiol, 101080. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41049512


Sotiridis, A., Dardamanis-Aidonas, C., Makris, A., Loukas, I., Geladas, N. and Koskolou, M. (2025). Tobacco smoking: A stimulus for blood volume expansion. Respir Physiol Neurobiol, 104505. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41093086


Zhang, J., Sun, J., Xu, Y., Jing, H., Zhang, L. and Chen, W. (2025). Different change patterns and sex difference for stroke and its subtypes mortality attributable to tobacco in China from 1990 to 2021. BMC Public Health, 1, 3189. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41029600


Zografou, A., Lachanas, G., Paparidou, R., Kourti, O., Antoniadou, V., Oikonomopoulou, I., Sanidas, E. and Thomopoulos, C. (2025). Prediction of blood pressure response through arterial stiffness in 'supersized smokers' undergoing renal denervation: a needle in a haystack. J Hypertens, 11, 1899. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41029985


Afolabi, S. O., Olaoye, S. O., Nyamgee, A. and Njan, A. A. (2025). Comparative effects of alternate tobacco products and traditional tobacco smoking on various organ/systems: A guide to regulators and health policy makers. Toxicol Rep, 102100. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40988706


Dahlgren, A., Erlinge, D., Torii, R., Yong, E., Bergstrom, G., Jernberg, T., Frobert, O., Thrane, P. G., Maeng, M., Stone, G. W. and Mohammad, M. A. (2025). Smoking and Coronary Atherosclerosis: Disproportionate Impact on the Right Coronary Artery. J Soc Cardiovasc Angiogr Interv, 8, 103609. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41019904


Ding, S. R., Patel, K., Chaparala, S. P., Pendyala, P. and Rani, K. (2025). Association Between Smoking and Stroke: A Retrospective Study Using the 2022 Behavioral Risk Factor Surveillance System (BRFSS) Data. Cureus, 7, e89171. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40900980


Hu, H., Nakagawa, T., Honda, T., Yamamoto, S., Okazaki, H., Ide, H., Dohi, S., Miyamoto, T., Yamamoto, M., Gommori, N., Kochi, T., Ogasawara, T., Konishi, M., Kabe, I. and Mizoue, T. (2025). Joint Impact of Smoking and Metabolic Syndrome on Cardiovascular Disease: A Cohort Study. J Atheroscler Thromb. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40887303


Jain, A., Huhulea, E. N., Thorman, I. B., Beazoglou, M., Spirollari, E., Sacknovitz, A., Soldozy, S., Frid, I., Thapa, S., Schubert, M. C., Ramakrishnan, P., Okafo, U., Tyagi, R., Gandhi, C. D. and Al-Mufti, F. (2025). Clinical Outcomes of Subarachnoid Hemorrhage in Patients With Nicotine Dependence: A Longitudinal Study of 43 315 Patients. Neurosurgery. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40891853


Kunutsor, S. K., Rikhtehgaran, R., Touw, D. J., Dullaart, R. P. F. and Bakker, S. J. L. (2025). Self-reported smoking, urine cotinine, and risk of incident hypertension: findings from the PREVEND prospective cohort study. J Hum Hypertens. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40993343


Parati, G., Salvi, P. and Ochoa, J. E. (2025). Smoking and central haemodynamics: new insights from the Framingham Heart Study. Eur J Prev Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40888810


Rahini, S., Raj, S., Mal, P., Gupta, M. and Goel, S. (2025). Association between Tobacco Use and Hypertension among Women of Prime Childbearing Age (20-34 Years) in India: Insights from National Family Health Survey-5 Data. Indian J Public Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40964762


Sun, L., Yu, H., Chen, D., Qin, D., Shi, Y., Hu, Y., Gao, J., Xie, C., Chen, X. and Wang, H. (2025). The impact of Shanghai's comprehensive smoke-free legislation on hospitalization and mortality rates of ischemic heart disease: An interrupted time series analysis. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41000450


Yang, R., Zheng, Y., Yu, H., Wu, J., Wang, S., Chen, H., Wang, M., Qin, X., Wu, T., Chang, C., Wu, Y. and Hu, Y. (2025). Impact of comprehensive tobacco control policies on stroke and acute myocardial infarction among patients with hypertension and type 2 diabetes in Beijing, China: An interrupted time-series analysis. Addiction. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40887313


Zheng, L., Baroom, G., Naqvi, R. E. Z., Heath, A. K., Berlanga-Taylor, A., Hibino, M. and Aune, D. (2025). Tobacco smoking and the risk of aortic aneurysm in the UK biobank. Sci Rep, 1, 32191. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40890428


Akl, E., Zeitoun, R., Chehab, O., Varadarajan, V., Li, H., Wu, C., Bertoni, A. G., Watson, K. E., Bluemke, D. A., Venkatesh, B. A. and Lima, J. A. C. (2025). Sex-Difference of Associations between Cigarette Smoking and Myocardial Fibrosis: The Multi-Ethnic Study of Atherosclerosis. medRxiv. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40766147


Brophy, J. M. (2025). A Protective Effect of Smoking on Repeat Revascularization: Another Example of Collider Stratification Bias. JACC Cardiovasc Interv. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40778890


Fabre, K. L. and Nazir, N. T. (2025). When the Smoke Clears: The Enduring Threat of Tobacco in Stable Coronary Artery Disease. Eur J Prev Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40795050


Gallimore, H., Paddock, S. and Vassiliou, V. S. (2025). When smoke gets to your heart - carbon monoxide-induced atrial fibrillation. Oxf Med Case Reports, 8, omaf132. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40809166


Hassan, W., Nabi, R., Rath, S., Javeid, A., Ali, D., Haseeb, B., Javeid, J., Abbasi, S., Inam, S. H. A., Serrano, E., Ahmed, R. and Ferguson, P. (2025). Stroke-Related Mortality Trends Among Tobacco Users in the U.S.: A 21-Year Retrospective Analysis of National Data from the CDC WONDER Database. J Stroke Cerebrovasc Dis, 108436. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40848956


Kim, Y. G., Jeong, J. H., Han, K. D., Roh, S. Y., Seo, C. O., Kim, Y., Lee, H. S., Shim, J., Kim, Y. H. and Choi, J. I. (2025). Smoking and the risk of sudden cardiac arrest in young-aged adults: a Korean nationwide population-based study. Eur J Prev Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40879661


Peris-Camarasa, B., Garrido, I. C., Pardo, O., Esteve-Turrillas, F. A., Dualde, P. and Coscolla, C. (2025). Smoking-induced increasing of oxidative stress in Spanish adults: A urinary biomonitoring study. Environ Toxicol Pharmacol, 104798. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40834991


Takeda, K., Aotani, D., Hashimoto, H., Hamada, K., Hasegawa, C., Shimizu, Y., Kuga, Y., Ando, T., Yagi, T., Koyama, H., Takagi, H., Shiraki, S., Yokochi, T., Kamiya, T., Kataoka, H. and Tanaka, T. (2025). Association of Heavy Smoking With High Body Mass Index and Cardiovascular Risk Score in Japan. Obes Sci Pract, 4, e70089. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40821910


Yang, N., Liu, T., Long, H., Chen, R., Zhu, Z., Wang, Y. and Xiao, H. (2025). Global burden of male smoking-induced stroke, 1990-2021, and 20-year projections: an analysis of the 2021 Global Burden of Disease Study. BMC Public Health, 1, 2694. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40775763


Zhang, S., Hua, Z., Li, Z., Cao, H. and Cheng, S. (2025). Global trends and inequities in smoking-attributable aortic aneurysm burden from 1990 to 2021 with future projections. Front Public Health, 1652544. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40800016


Altiparmak, T., Batur Caglayan, H. Z., Kesen Ozbek, S., Oncu, F., Karabork Kilic, A. C., Erdogan, T., Yaymaci, S. and Nazliel, B. (2025). The Influence of Smoking and Systemic Inflammation on Carotid Artery Disease: A Cross-Sectional Analysis of Stenosis, Plaque Surface Characteristics. Angiology, 3.31973E+13. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40697003


Ansari, S., Trujillo, R., McClelland, R. L. and Budoff, M. J. (2025). Aortic arch calcification in relation to cigarette smoking: results from the multi-ethnic study of atherosclerosis (MESA). Int J Cardiovasc Imaging. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40694200


Bianchi, L., Damiani, I., De Salvo, R., Rossi, C., Carleo, A., D'Alonzo, C., Bini, L., Corsini, A. and Bellosta, S. (2025). Differential effects of traditional cigarette, electronic cigarette, and tobacco heating product on human vascular smooth muscle cell phenotypic switch: A comparative functional perspective. Atherosclerosis, 120412. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40614667


Bobbio, E. and Limongelli, G. (2025). Smoke signals of risk in the young: rethinking sudden cardiac arrest in the era of preventive inertia. Eur J Prev Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40711390


Makena, P., Haswell, L. E., McEwan, M., Keyser, B. M., Smart, D. E., Leverette, R., Jordan, K., Breheny, D. and Baxter-Wright, S. (2025). An adverse outcome pathway for cigarette smoke-mediated oxidative stress in plaque formation. Front Toxicol, 1554747. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40661062


Mu, Y. and Xia, J. (2025). Exploring the impact of smoking on coronary heart disease risk in women: Insights from the NHANES database. Medicine (Baltimore), 29, e43324. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40696673


Nakai, M., Iwanaga, Y. and Fujiwara, H. (2025). Association between partial smoking ban legislation and acute coronary syndrome: A nationwide analysis. J Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40633658


Shao, J., Song, G., Hu, Y., Niu, Q. and Yan, Y. (2025). Estimating the Global Burden and Health Risks Associated with Dietary and Cigarette-Related Cadmium Exposure. Biol Trace Elem Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40705220


Yuan, S., Khodursky, S., Geng, J., Sharma, P., Spin, J. M., Tsao, P., Levin, M. G. and Damrauer, S. M. (2025). Circulating Protein Mediators Linking Genetically Predicted Smoking to Abdominal Aortic Aneurysm: A Genomic-Proteomic Analysis. Arterioscler Thromb Vasc Biol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40671653


Alqahtani, J. S., Aldhahir, A. M., Alqarni, A. A., Alghamdi, S. M., Oyelade, T., Alzaidi, F. N., Alamri, M. A., Kheder, A. M., Alsamdani, H. I., AlAyadi, A. Y., Siraj, R. A., Aldabayan, Y. S. and Al Rajeh, A. M. (2025). Understanding of Stroke Risk Among Smokers in Saudi Arabia. Medicina (Kaunas), 6. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40572695


Chen, S., Lv, T., Li, W., Yu, L., Pan, G. and Shen, T. (2025). Joint associations of PM(10) and smoking with the risk of new-onset stroke in middle-aged and older adult Chinese adults: findings from the CHARLS cohort study. Front Public Health, 1537166. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40529701


Hei, B., Liu, J., Fang, J., Gao, Q., Wang, B., Zhou, W. and Zhou, J. (2025). Changing patterns of stroke and subtypes attributable to smoking from 1990 to 2021 in China and projections to 2050. J Stroke Cerebrovasc Dis, 8, 108368. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40480483


Alqahtani, J. S., AlDraiwiesh, I. A., Aldhahir, A. M. and Oyelade, T. (2025). Burden of smoking-related stroke in Saudi Arabia: trends from 1990 to 2021. PLoS One, 5, e0324039. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40435184


Jabbarli, R., Darkwah Oppong, M., Gumus, M., Chihi, M., Dinger, T. F., Rauschenbach, L., Ahmadipour, Y., Dammann, P., Li, Y., Guberina, N., Wrede, K. H. and Sure, U. (2025). Impact of lifetime and current smoking exposure on the rupture status, number, and size of intracranial aneurysms. Clin Neurol Neurosurg, 108924. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40339192


Mustra Rakic, J., Pullinger, C. R., Van Blarigan, E. L., Movsesyan, I., Stock, E. O., Malloy, M. J. and Kane, J. P. (2025). Increased prevalence of coronary heart disease among current smokers carrying APOL1 risk variants within the African American population. J Clin Lipidol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40360375


Osman, H., Schlettert, C., Materzok, D., Akin, M., Abumayyaleh, M., Akin, I., Mugge, A., Aweimer, A., Hamdani, N. and El-Battrawy, I. (2025). Impact of smoking in MINOCA patients. Eur J Clin Invest, e70054. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40342090


Welsh, P., Pouncey, A. L., Sattar, N. and Powell, J. T. (2025). Sex-Specific Risk of Smoking for Abdominal Aortic Aneurysm and Exploration of Potential Mechanism: Meta-Analysis and Prospective Cohort Study. Arterioscler Thromb Vasc Biol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40336481


Zhao, J., Hong, H., Zhai, J., Poudel, R., Srivastava, S., Stokes, A. C., Lorkiewicz, P. K., Jiang, T., Robertson, R. M., Bhatnagar, A., Hall, J. L., Hamburg, N. M. and Keith, R. J. (2025). Clustering analysis of volatile organic compound biomarkers with tobacco exposure and the association with cardiovascular health outcomes in an observation study cohort. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40386170


Zhu, X., Chen, L., Yang, X., Du, Y., Zhao, Y., Hu, T., Sun, N., Sun, Q., Liang, W., Wei, X. and Zhang, Z. (2025). Global, regional, and national trends in tobacco-induced cardiovascular disease burden for 1990-2021 with projections to 2045: A comprehensive analysis based on the Global Burden of Disease Study 2021. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40376198


Abbas, F. A., Batool, S., Hina, M., Khalid, T., Aman, A., Awan, F. R. and Hussain, M. (2025). Impact of Gene-Smoking Interaction on Risk of Atherosclerosis: Molecular Study of Prothrombin (F2) Gene rs1799963 G/A Polymorphism in Atherosclerotic Patients. Cardiovasc Toxicol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40261540


Alhindal, M., Janahi, J., D'Angelo, E. C., Lisignoli, V., Palmieri, R., Cutri, A., Butera, G., Gatzoulis, M. A. and Montanaro, C. (2025). Impact of smoking on cardiovascular health: Mechanisms, epidemiology and specific concerns regarding congenital heart disease. Int J Cardiol Congenit Heart Dis, 100581. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40242035


Antignani, P. L., Poredos, P., Blinc, A., Cevc, M., Stanek, A., Jawien, A. and Mansilha, A. (2025). Smoking and lower extremity artery disease. Int Angiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40178801


Benowitz, N. L. (2025). Predicting Cardiovascular Risk With Use of Various Tobacco Products. Circulation, 14, 1006-1008. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40193542


Ding, C., Yuan, M., Cheng, J. and Wen, J. (2025). Cross-sectional study on smoking types and stroke risk: development of a predictive model for identifying stroke risk. Front Physiol, 1528910. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40196720


Franco, L., Gallego, N., Velarde, C., Valencia, D., Perez-Bedoya, J. P., Betancur, K., Marisancen, K., Parra, P., Carvalho, S., Parra, L., Jimenez, E., Martinez, C., Saldarriaga, C., Arango, J. C., Gonzalez-Jaramillo, N., Garcia, J. and Valencia, A. (2025). Variants in candidate genes and their interactions with smoking on the risk of acute coronary syndrome. Biomedica, 1, 107-117. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40257950


Kadakia, K. T. and Krumholz, H. M. (2025). FDA's Proposed Nicotine Regulations: A New Frontier for Cardiovascular Health. J Am Coll Cardiol, 13, 1459-1461. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40175018


Khan, M. Y. I., Dillman, A., Sanchez-Perez, M., Hibino, M. and Aune, D. (2025). Tobacco smoking and the risk of aortic dissection in the UK Biobank and a meta-analysis of prospective studies. Sci Rep, 1, 12083. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40204884


Mesnier, J., Giovachini, L., Ducrocq, G., Danchin, N., Ford, I., Tendera, M., Feldman, L. J., Ferrari, R., Tardif, J. C., Fox, K. M., Vidal-Petiot, E. and Steg, P. G. (2025). Smoking Trajectories and Residual Cardiovascular Risk in Patients with Stable Coronary Artery Disease: An international Cohort Study. Eur J Prev Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40250842


Mohseni, P., Khalili, D., Niknam, M. and Izadi, N. (2025). The interplay of physical activity and smoking with metabolic syndrome and its components in the STEPS survey. Sci Rep, 1, 12590. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40221524


Yesildag, M., Keskin, Z., Yavsan, D. M., Bekci, T. T. and Osmanoglu, U. O. (2025). The Effects of Smoking and Airway Restriction on Subclinical Atherosclerosis. Int J Chron Obstruct Pulmon Dis, 1217-1226. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40297844


Galvin, O., Nasir, K. and McEvoy, J. W. (2025). The Cardiovascular Epidemiology of Smoking: Past, Present, and Future. J Am Coll Cardiol, 10, 1035-1037. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40074468


Ji, Y., Lv, N. and Dang, A. (2025). Association of Smoking and Alcohol with Abdominal Aortic Calcification in the General Middle-Aged and Elderly Populations. Rev Cardiovasc Med, 3, 26087. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40160599


Khimani, A., Hornback, A., Jain, N., Avula, P., Jaishankar, A. and Wang, M. D. (2024). Predicting Cardiovascular Disease Risk in Tobacco Users Using Machine Learning Algorithms. Annu Int Conf IEEE Eng Med Biol Soc, 1-May. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40039995


Li, X., Song, S., Jia, W., Shi, Z., Xie, L., Fan, M. and Li, C. (2025). Do CRP gene variants and smoking elevate recurrent stroke risk in minor ischemic stroke patients?. Eur J Med Res, 1, 179. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40098137


Marcos-Garcia, L., Clara, A., Perez-Cabezon, S., Miralles-Hernandez, M., Elosua, R. and Velescu, A. (2025). Association between DNA methylation at smoking-related loci and mortality in patients with peripheral arterial disease. Rev Esp Cardiol (Engl Ed). Available from: https://www.ncbi.nlm.nih.gov/pubmed/40122233


Tiwari, S., Lovsletten, O., Jacobsen, B. K., Wilsgaard, T., Mathiesen, E. B., Schirmer, H., Gram, I. T., Mannsverk, J. and Lochen, M. L. (2025). Occasional smoking is a risk factor for myocardial infarction in the population-based Tromso Study, 2001-2021. Eur J Prev Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40146252


Yao, Z., Tasdighi, E., Dardari, Z. A., Jha, K. K., Osuji, N., Rajan, T., Boakye, E., Rodriguez, C. J., Matsushita, K., Simonsick, E. M., Lima, J. A. C., Widome, R., Cohen, D. L., Appel, L. J., Khera, A., Hall, M. E., Judd, S. E., Cole, S. A., Vasan, R. S., Benjamin, E. J., Lotufo, P. A., Bensenor, I. M., El Khoudary, S. R., Barinas-Mitchell, E., Janssen, I., Psaty, B. M., Eaton, C. B., LaMonte, M. J., Cawthon, P. M., Orwoll, E. S., Irvin, M. R., Bhatnagar, A., DeFilippis, A. P., El-Shahaway, O. and Blaha, M. J. (2025). Association Between Cigarette Smoking and Subclinical Markers of Cardiovascular Harm. J Am Coll Cardiol, 10, 1018-1034. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40074467


Yuan, S., Khodursky, S., Geng, J., Sharma, P., Spin, J. M., Tsao, P., Levin, M. G. and Damrauer, S. M. (2025). Identifying Circulating Protein Mediators in the Link Between Smoking and Abdominal Aortic Aneurysm: An Integrated Analysis of Human Proteomic and Genomic Data. medRxiv. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40061319


Aragiannis, D., Kasiakogias, A., Iliakis, P., Sagris, M., Tatakis, F. P., Manta, E., Andrikou, I., Konstantinidis, D. and Tsioufis, K. (2025). The Combined Effect of Smoking and Obesity on Hypertension: Implications for Clinical Management. Curr Hypertens Rev. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39950475


Aslam, M. A., Iqbal, H., Ilyas, K., Rehman, K., Hussain, A., Akash, M. S. H., Shahid, M. and Chen, S. (2025). Metabolomic Insights into Smoking-Induced Metabolic Dysfunctions: A Comprehensive Analysis of Lipid and Amino Acid Metabolomes. Metabolites, 2. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39997721


Farhoud, A., Mahamid, I., Najjar, M., Owda, A., Safarini, O., MohammedAli, M., Thabaleh, A., Mousa, A., Zarour, A., Alhabil, Y., Suadi, L., Nazzal, Z. and Damiri, B. (2024). Risk of metabolic syndrome linked to tobacco smoking and caffeine consumption among Palestinian university students. Cent Eur J Public Health, 4, 243-250. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39903594


Ghozy, S., Jazayeri, S. B., Hasanzadeh, A., Ognard, J., Kobeissi, H., Ahmadzade, A., Naseh, E., Fard, M. M., Abbas, A. S., Borkar, R. R., Kallmes, D. F. and Kadirvel, R. (2025). Impact of Smoking on Recurrence and Angiographic Outcomes After Endovascular Treatment of Intracranial Aneurysms: A Systematic Review and Meta-Analysis. AJNR Am J Neuroradiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39984186


Kumar, B., Mathur, T., Annepu, Y. R., Annepu, K. K. and Chaitanya, P. D. K. (2024). Exploring the Interplay of Smoking Behavior, Heart Rate Variability, Pulmonary Function Test Results, Diabetes, and Mood Disorders: A Systematic Review. J Pharm Bioallied Sci, Suppl 4, S3092-S3095. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39926888


Schwalb, M. E., McEvoy, J. W., Navas-Acien, A., Wallace, A. S., Rooney, M. R., Selvin, E., Christenson, R. H. and Jones, M. R. (2025). Tobacco Exposure and Markers of Myocardial Stress and Damage Among US Adults. Am J Cardiol, 19-21. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39894331


Siegel, N. A., Zhao, J., Benjamin, E. J., Bhatnagar, A., Hall, J. L. and Stokes, A. C. (2025). Identifying Patterns of Tobacco Use and Associated Cardiovascular Disease Risk Through Machine Learning Analysis of Urine Biomarkers. JACC Adv, 3, 101630. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39985885


Wu, X., Liu, Y., Zou, C., He, F., Guo, F., Liu, S., Fan, Y., Zhu, X., Zhou, Q. and Shu, D. (2024). Nicotine's impact on platelet function: insights into hemostasis mechanisms. Front Pharmacol, 1512142. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39902074


Ye, X., Wu, Q., Lv, Q., Hou, X., Yang, Y., Yang, C. and Wang, S. (2025). Smoking, Alcohol Consumption, and Atrial Fibrillation: Mendelian Randomization Study. Cardiovasc Toxicol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39987412


Cao, S., Zeng, Y., Pang, K., Chen, M., Guo, R., Wu, N., Fang, C., Deng, H., Zhang, X., Xie, X., Ouyang, W. and Yang, H. (2025). Unraveling the causal impact of smoking and its DNA methylation signatures on cardiovascular disease: Mendelian randomization and colocalization analysis. Clin Epigenetics, 1, 1. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39748436


Gaalema, D. E., Zhang, Y., Howard, G. and Menson, K. (2025). Patient Characteristics and Outcomes by Sex and Smoking Status in Pulmonary and Cardiac Rehabilitation. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39787043


Kaszuba, M., Koscielniak, J., Sliwka, A., Pilinski, R., Bochenek, G., Maga, P. and Nowobilski, R. (2025). The prevalence of chronic obstructive pulmonary disease in hospitalized tobacco smokers with peripheral artery disease. Vasa. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39829220


Komurcu, H. F., Sever, N., Gokdereli, N. S., Keske, O. and Gozke, E. (2025). The relationship between smoking and clinical outcome in ischemic stroke patients undergoing reperfusion therapy. Neurol Res, 2, 87-95. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39749740


Kuang, Z., Lin, L., Kong, R., Wang, Z., Mao, X. and Xiang, D. (2025). The correlation between cumulative cigarette consumption and infarction-related coronary spasm in patients with ST-segment elevation acute myocardial infarction across different age groups. Sci Rep, 1, 253. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39747215


Kwak, J. H. and Kim, H. J. (2024). High air pollution exposure, vitamin D deficiency and ever smokers were associated with higher prevalence of hypercholesterolemia: A cross-sectional study from the 2008-2014 Korea National Health and Nutrition Examination Survey. Nutr Res, 1-Dec. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39799634


Liu, F. F., Yan, Y. X., Zhang, H. F. and Li, K. (2025). Gene Expression Signatures of Smoking and Acute Myocardial Infarction: A Blood Transcriptome Analysis. Mediators Inflamm, 2431090. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39845197


Masengere, P., Halbesma, N., Ndejjo, R., Balugaba, B. E., Wanyenze, R. K., Nuwaha, F., Bastiaens, H. and Musinguzi, G. (2025). Additive interaction of conjoint tobacco smoking and heavy drinking on hypertension prevalence in rural Uganda: a community-based cross-sectional study. BMC Public Health, 1, 201. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39833763


Mons, U., Lohner, V. and Seuthe, K. (2025). Trends in smoking-attributable cardiovascular mortality in Germany. Eur J Public Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39761513


Nieto Iglesias, J., Martinez de Salinas, A. P., Perez-Monteoliva, N. R. R. and En representacion del Grupo de Prevencion de Riesgo Renal y Vascular de la Sociedad Espanola de, N. (2025). Some thoughts about the "Consensus statement on smoking and vascular risk" from the Spanish Autonomous Societies of Hypertension and Vascular Risk. Nefrologia (Engl Ed), 1, 1-Apr. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39799082


Pizziolo, P. G., Clemente, L. M., Ribeiro, A. B., Oliveira, V. C., Macedo, A. P., Salgado, H. C., Fazan-Junior, R., Watanabe, E., Silva-Lovato, C. H. and Ribeiro, A. B. (2025). The interplay of edentulism, smoking, microbiota, oral rehabilitation on cytokineprofile and different conditions of hypertension. Arch Oral Biol, 106176. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39827717


Vaishnav, D., Essibayi, M. A., Musmar, B., Adeeb, N., Salim, H. A., Aslan, A., Cancelliere, N. M., McLellan, R. M., Algin, O., Ghozy, S., Lay, S. V., Guenego, A., Renieri, L., Carnevale, J., Saliou, G., Mastorakos, P., El Naamani, K., Shotar, E., Premat, K., Mohlenbruch, M., Kral, M., Doron, O., Chung, C., Salem, M. M., Lylyk, I., Foreman, P. M., Vachhani, J. A., Shaikh, H., Zupancic, V., Hafeez, M. U., Catapano, J., Waqas, M., Ayberk, G., Celal Gunes, Y., Rabinov, J. D., Ren, Y., Schirmer, C. M., Piano, M., Kuhn, A. L., Michelozzi, C., Elens, S., Starke, R. M., Hassan, A. E., Ogilvie, M., Nguyen, A., Jones, J., Brinjikji, W., Nawka, M. T., Psychogios, M., Ulfert, C., Diestro, J. D. B., Pukenas, B., Burkhardt, J. K., Huynh, T., Martinez-Gutierrez, J. C., Sheth, S. A., Spiegel, G., Tawk, R. G., Lubicz, B., Panni, P., Puri, A. S., Pero, G., Nossek, E., Raz, E., Killer-Oberpfalzer, M., Griessenauer, C. J., Asadi, H., Siddiqui, A., Brook, A. L., Haranhalli, N., Ducruet, A. F., Albuquerque, F. C., Regenhardt, R. W., Stapleton, C. J., Kan, P., Kalousek, V., Lylyk, P., Boddu, S., Knopman, J., Aziz-Sultan, M. A., Tjoumakaris, S. I., Clarencon, F., Limbucci, N., Cuellar-Saenz, H. H., Jabbour, P. M., Mendes Pereira, V., Patel, A. B., Altschul, D. J., Dmytriw, A. A. and WorldWide, W. E. B. C. (2025). Impact of smoking on recurrence rates among wide-neck intracranial aneurysms treated with Woven EndoBridge: a multicenter retrospective study. J Neurosurg, 1-Sep. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39889291


Wang, Y., Li, Q., Bi, L., Wang, B., Lv, T. and Zhang, P. (2025). Global trends in the burden of ischemic heart disease attributable to smoking from 1990 to 2021: A systematic analysis of the Global Burden of Disease Study 2021. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39882032


Xiao, C., Wang, J., Cheng, Z., Gong, J. and Yu, C. (2025). Stroke Subtypes Mortality Attributable to Smoking in China: A Study Based on the Global Burden of Disease Database 2021. Neuroepidemiology, 1-Aug. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39809251


Agbaje, A. O. (2024). Incidental and Progressive Tobacco Smoking in Childhood and Subsequent Risk of Premature Cardiac Damage. J Am Coll Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39665696


Amirzada, M. Z., Sahrai, M. S., Hayat, M. S., Ishaq, N., Yasin, A. G., Ahadi, A. N., Fazli, N. and Wasiq, A. W. (2024). Associations of tobacco use, physical activity and diet with hypertension in the city of Kandahar, Afghanistan: a community-based cross-sectional study. BMC Res Notes, 1, 385. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39722005


Balu, A. and Lip, G. Y. H. (2024). The Impact of Atrial Fibrillation and Smoking History on Brain Deficits. Am J Cardiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39674440


Chauhan, D., Patel, D., Yogesh, M. and Trivedi, N. (2024). Health literacy and tobacco cessation among hypertensive individuals: A mixed method study. J Educ Health Promot, 380. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39703660


Ghoche, M. T., Maroufi, S. F., El Maalouf, J. M., Pachon-Londono, M. J., Nguyen, B. A., Halpin, B. S., Turcotte, E. L., Patra, D., Krishna, C., Wang, Z., Turkmani, A., Ogilvy, C. S. and Bendok, B. R. (2024). Impact of smoking on the detection of brain aneurysms in general population screening: a systematic review and meta-analysis. J Neurosurg, 1-Sep. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39729618


Irfan, A., Riggs, D. W., Koromia, G. A., Gao, H., DeFilippis, A. P., Soliman, E. Z., Bhatnagar, A. and Carll, A. P. (2024). Smoking-associated electrocardiographic abnormalities predict cardiovascular mortality. Sci Rep, 1, 31189. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39730843


Jarvensivu-Koivunen, M., Hernesniemi, J. and Tynkkynen, J. (2025). Smoking and sudden cardiac death in patients with previous coronary artery disease. Coron Artery Dis, 1, 59-64. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39652651


Khabbazi, A., Rahimi, M., Malek Mahdavi, A., Farzaneh, R., Daneshvar, S., Naseri, A., Beig Zali, S. and Nasiri, E. (2024). Insights into the paradoxical effect of smoking on vasculitis: a comprehensive review. Sarcoidosis Vasc Diffuse Lung Dis, 4, e2024053. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39655594


Lakicevic, S., Bender, M., Lakicevic, G., Jurina, R., Mihic, N. and Malojcic, B. (2024). The Influence of Tobacco Smoking Intensity on Hemodynamic Parameters: A Functional Transcranial Doppler Study on Vascular Reserve in Chronic Smokers. Cureus, 11, e72956. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39640160


Li, Y., Tong, L., Zhang, Y., Huang, B. and Zhu, L. (2024). Comprehensive Mendelian Randomization Analysis of Smoking and Its Effects on Venous Thromboembolism. Semin Thromb Hemost. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39689867


Litvinov, E. and Litvinov, A. (2024). The Relationship Between Periodontitis, Gingivitis, Smoking, Missing Teeth, Endodontic Infections, Aortic Aneurysm, and Coronary Artery Disease: The 10-Year Results of 25 Patients. Cureus, 11, e73584. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39677218


Ma, M., Wu, Y., He, X., Zhang, M., Han, Y., Guo, R. and Li, S. (2024). Associations between smoking and coronary heart disease: mediating role of RDW. Front Public Health, 1447303. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39618953


Merzah, M., Poliska, S., Balogh, L., Sandor, J. and Fiatal, S. (2024). Smoking-Associated Changes in Gene Expression in Coronary Artery Disease Patients Using Matched Samples. Curr Issues Mol Biol, 12, 13893-13902. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39727958


Tani, S., Imatake, K., Suzuki, Y., Yagi, T. and Takahashi, A. (2024). Total serum bilirubin levels as mediators of anti-atherosclerosis mechanisms with consideration of smoking status. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39619739


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2