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3.13 Musculoskeletal diseases
Foreword

Relevant news and research: Musculoskeletal conditions

Sagelv, E. H., Winther, A., Emaus, N., Evensen, E., Christoffersen, T., Dennison, E., Furberg, A. S., Johansson, J. and Nilsen, O. A. (2025). Does tobacco use influence bone mineral density levels in a Norwegian youth cohort followed from adolescence to young adulthood? The Fit Futures Study (2010-2022). BMJ Open, 8, e101654. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40887122


Xie, W., Song, C., Hao, P., Li, F., Hou, X., Chen, J., Liu, Z. and Wang, Z. (2025). Analysis of the toxicity and mechanisms of osteoporosis caused by cigarette toxicants using network toxicology and molecular docking techniques. Sci Total Environ, 180414. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40925315


Kiraz, M. and Kina, H. (2025). Effect of Long-Term Smoking on Cervical Disc Degeneration: A Retrospective Study. Med Sci Monit, e949466. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40851288


Andrade, J. P., de Oliveira, M. C. A., Porto, A. C. S., Martins, G. M. T., Campos, N. M., Neto, P., de Almeida, C. B., Meira, S. S., da Silva, D. J., Casotti, C. A. and Dos Santos, L. (2025). Advanced age, tobacco use, insufficient physical activity, and high sedentary behavior associated with lower limb muscle weakness in older adults: A cross-sectional study. Geriatr Nurs, 103508. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40738043


Dou, X., He, M., Wang, Y., Huang, Y., Zhang, Z., Lin, H. and Yang, Y. (2025). Early-life exposure to tobacco, inflammation, and risk of rheumatic diseases: a prospective cohort study. J Public Health (Oxf). Available from: https://www.ncbi.nlm.nih.gov/pubmed/40611489


Hussain, M. S., Islam, T., Islam, M. S., Danishuddin and Haque, M. A. (2025). Clinical insights into the role of smoking, diabetes, and rheumatoid arthritis in osteoporotic fractures. Arch Osteoporos, 1, 87. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40643730


Wang, B., Zhang, J., Du, P., Ke, H., Zang, L. and Yuan, S. (2025). Global burden of low back pain attributable to smoking in 204 countries and territories in 1990-2021. Front Public Health, 1584659. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40709036


Wolf, B. R., Hettrich, C. M., Van Tienderen, R. J., Rossow, J., Glass, N., Ortiz, S. F. and Group*, M. S. (2025). Differences Between Smokers and Non-Smokers Undergoing Surgery for Anterior Shoulder Instability in the Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Cohort. Iowa Orthop J, 1, 153-159. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40606702


Kerget, B., Taskin, B., Aksakal, A., Ozkan, H. B. and Ucar, E. Y. (2025). Muscle oxygenation levels in smokers and non-smokers during exercise: insights from a university-based study. Eur J Appl Physiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40515840


Petersson, M., Jons, D., Feresiadou, A., Ilinca, A., Lundin, F., Johansson, R., Budzianowska, A., Roos, A. K., Kagstrom, V., Gunnarsson, M., Sundstrom, P., Klareskog, L., Olsson, T., Kockum, I., Piehl, F., Alfredsson, L. and Brauner, S. (2025). Nicotine, Alcohol Consumption, and Risk of Myasthenia Gravis: Results From the Swedish Nationwide GEMG Study. Neurology, 1, e213771. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40493875


Son, H. J., Park, S. J., Park, J. S. and Han, K. (2025). Impact of smoking, diabetes, and exercise on dementia risk in women with osteoporosis: a nationwide cohort study. Osteoporos Int. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40493245


Zeng, J. and Zhou, Z. (2025). Expanding the smoking-chronic musculoskeletal pain nexus: beyond toxicants to behavioral and psychological factors. Pain, 7, 1707-1708. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40532074


Lee, S. R., Lee, S. Y., Park, E. J., Lee, Y., Choi, J. I., Kwon, R. J., Son, S. M., Gyu Lee, J., Yi, Y. H., Tak, Y. J., Lee, S. H., Kim, G. L., Ra, Y. J. and Cho, Y. H. (2025). Association between cumulative pack-year smoking exposure and sarcopenia: a KoGES cohort study. Int J Epidemiol, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40338529


Schonnagel, L., Hoehl, B. U., Taheri, N., Becker, L., Suwalski, P., Schomig, F., Kohli, P., Schmidt, H. and Pumberger, M. (2025). The Impact of Smoking on Low Back Pain and Disability. Eur J Pain, 6, e70041. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40392623


Li, H., Kelley, J., Ye, Y., Ye, Z. W., Townsend, D. M., Zhang, J. and Wu, Y. (2025). REDOX Imbalance and Oxidative Stress in the Intervertebral Disc: The Effect of Mechanical Stress and Cigarette Smoking on ER Stress and Mitochondrial Dysfunction. Cells, 8. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40277939


Qu, X., Jiang, J., Deng, Q., Wang, H., Zhang, C., Xu, X., Yi, Y. and Qiu, L. (2025). Associations between smoking and osteoporosis and all-cause mortality in participants from the United States: a cohort study. Front Endocrinol (Lausanne), 1533633. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40196462


Sha, T., Zhang, Y., Joshi, A. D., Lane, N. E., Wei, J., Li, W., Xie, H., Li, J., Li, C., Zeng, C., Lei, G. and Wang, Y. (2025). Smoking, alcohol and risk of sarcopenia: a Mendelian randomisation study. BMJ Open, 4, e091656. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40194871


Sweis, N., Dominati, A., Prasad, S., Alnaimat, F., Alawqati, M., Rubinstein, I. and Caskey, R. (2025). Tobacco smoking and sarcoidosis revisited - evidence, mechanisms, and clinical implications: a narrative review. Curr Med Res Opin, 26-Jan. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40257453


Cetin, E., Basgul Sagiri, D., Kahraman Ozlu, E. B., Akar, E., Guler, E. M., Kocaoglu, S., Beyaztas, H. and Demir, E. (2025). Inflammatory Biomarkers in Smokers: Implications for Ligamentum Flavum Hypertrophy. Med Sci Monit, e947508. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40129026


Thibon, C., Caty, G., Gohy, S., Aboubakar Nana, F. and Reychler, G. (2025). Assessment of Muscular Strength and Functional Capacity in Smoker Population Without Any Diagnosed Respiratory Disease: A Cross-Sectional Study. Healthcare (Basel), 5. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40077055


Djade, C. D., Diorio, C., Laurin, D., Talbot, D., Carmichael, P. H. and Dionne, C. E. (2025). An examination of acrylamide and cadmium as possible mediators of the association between cigarette smoking and chronic musculoskeletal pain. Pain. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39907535


Xiao, Q., Dong, S., Tan, Y., Zhang, X., Yao, L., Li, Q. and Wang, T. (2025). The causal impact of smoking behavior on osteoarthritis: a Mendelian randomization analysis. Front Public Health, 1437443. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39916716


Shi, W., Wu, K., Li, H. and Zhang, H. (2025). Smoking may be a risk factor for carpal tunnel syndrome: Insights from Mendelian randomization analysis. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39886524


Wu, Y., Chao, J., Bao, M., Zhang, N. and Wang, L. (2025). Causal association among smoking, bitter beverage consumption, and risk of osteoporosis: a two-sample mendelian randomization-based study. Hereditas, 1, 7. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39856786


Fatica, M., Cela, E., Ferraioli, M., Costa, L., Conigliaro, P., Bergamini, A., Caso, F. and Chimenti, M. S. (2024). The Effects of Smoking, Alcohol, and Dietary Habits on the Progression and Management of Spondyloarthritis. J Pers Med, 12. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39728027


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

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Chapter 2