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5.3 Early biological factors
Foreword

Relevant news and research: Early biological factors

Apinis, P., Bajare, I., Dzerve, V., Jegere, S., Tzivian, L., Kokina, B., Luguzis, A., Caksa, A. and Erglis, A. (2026). Gender-Specific Trends and Determinants of Daily Smoking in Latvia (2009-2019): A Population-Based Cross-Sectional Study. Medicina (Kaunas), 6. Available from: https://www.ncbi.nlm.nih.gov/pubmed/42356212


Frisbee, S., Moran, M. B., Ibrahim, M., Czaplicki, L. and Kennedy, R. D. (2026). Tobacco marketing and youth perceptions: connections between industry tactics and beliefs about harm and addiction among those under 21. Subst Abuse Treat Prev Policy. Available from: https://www.ncbi.nlm.nih.gov/pubmed/42374583


Luo, M., Pons, V. T., Zakharin, M., Pingault, J. B., Gillespie, N. A. and van Loo, H. M. (2026). Indirect Genetic Effects on Alcohol Use Disorder and Nicotine Dependence. medRxiv. Available from: https://www.ncbi.nlm.nih.gov/pubmed/42064914


Dyer, W. G., Lee, S. H., Wilding, H., Sutara, B. and Lee, H. H. (2026). Synergistic Effects of Early Psychosocial Factors and Polygenic Risk for Smoking: a Cross-Sectional Analysis of a Sample of Older Adults in the United States. Dev Psychobiol, 3, e70152. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41917796


Gunn, M. P., Rose, G. M., Whitton, A. E., Pizzagalli, D. A. and Gilbert, D. G. (2026). Depression, anxiety, and genetics shape smoking risk through salience networks. Psychiatry Res Neuroimaging, 112202. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41950829


Liu, L. and Wang, X. (2026). Navigating Gendered Expectation: How Young Female Smokers in China Respond to Social Judgment. J Psychoactive Drugs, 1-9. Available from: https://www.ncbi.nlm.nih.gov/pubmed/42010790


Das, M., Nhem, M., John, M. E., Vogel, E. A. and Romm, K. F. (2026). Distinct Motives for Tobacco Use Among Rural Versus Urban Residing Sexual Minority Young Adults in Oklahoma and Surrounding States. Subst Use Addctn J, 29767342261426098. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41867142


Gvinianidze, K., Bakhturidze, G., Abuladze, T., Dekanosidze, A., Sturua, L., Gegenava, V., Tarasenko, Y. and Ciobanu, A. (2026). Gender trends in youth tobacco and nicotine use in Georgia across GYTS rounds, 2014-23. Eur J Public Health, 2. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41903329


Hackworth, E. E., Vidana-Perez, D., O'Neal, R., Hinds, J. T., Titus, A. R., Kim, M., Fillo, J., Hammond, D. and Thrasher, J. F. (2026). Association Between Mental Health and Nicotine/Tobacco Use by Disaggregated Gender Identities Among U.S. Adolescents, 2020-2023. LGBT Health, 23258292261422233. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41719096


Hossain, S., Beard, E., Kale, D., Mishu, M. P., Jackson, S., Cox, S. and Shahab, L. (2026). Prevalence and correlates of tobacco use among adolescents in Dhaka, Bangladesh: a cross-sectional study. BMC Public Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41761221


Alwardat, D. M., Saddik, B. and Sreedharan, J. (2026). Tobacco smoking habits, attitudes and associated factors among women in the United Arab Emirates. BMC Public Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41527030


McNealy, K. R., Barrett, S. T. and Bevins, R. A. (2026). We must look beyond primary reinforcement to understand nicotine use in women. Front Neuroendocrinol, 101231. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41529789


Salgin, L., Kellogg, D., Edusada, I., Lim, A. C., Velasquez, A., Helm, J., Blashill, A. J., Myers, M., Jun, H. J. and Calzo, J. P. (2026). An Ecological Momentary Assessment Protocol to Measure Stress, Socialization, and Other Contributors to Smoking Behaviors Among LGBTQ+ Adolescents: Multimethod Evaluation of Feasibility, Acceptability, and Appropriateness From the Puff Break Research Study. JMIR Form Res, e79957. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41564333


Xie, X., Di, X., Yin, X., He, W., Chan, S. S. C. and Xiao, L. (2026). Understanding female smoking in urban China: motivations, stigma and shifting social norms-a qualitative focus group study. BMJ Open, 1, e110684. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41617236


Adebisi, Y. A. and Alshahrani, N. Z. (2025). Functional disability and the risk of subsequent smoking initiation: A prospective cohort analysis. Addict Behav, 108588. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41412006


Albayrak, M. and Turhan, K. (2025). Genetic and Environmental Factors of Nicotine Addiction: Examination of Multiple Substance Addictions. Am J Med Genet B Neuropsychiatr Genet. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40859751


El Dalatony, M. M., Elkhobby, A. A., Shubayr, M. A., Monshi, S. S., Al-Zalabani, A. H., El Desouky, E. D., Aldukhail, S. K., Alqahtani, M. M., Alhazmi, A. S. and Aldossary, M. S. (2025). Prevalence and predictors of tobacco use among Saudi adolescents: the Global Youth Tobacco Survey (GYTS) 2022. BMC Public Health, 1, 2733. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40797248


Johnson, E. C., Lai, D., Balbona, J. V., Miller, A. P., Hatoum, A. S., Deak, J. D., Jennings, M., Baranger, D. A. A., Galimberti, M., Sanichwankul, K., Thorgeirsson, T., Colbert, S. M. C., Adhikari, K., Docherty, A. R., Degenhardt, L., Edwards, T., Fox, L., Giannelis, A., Jeffries, P. W., Korhonen, T., Morrison, C. L., Nunez, Y. Z., Palviainen, T., Su, M. H., Romero Villela, P. N., Wetherill, L., Willoughby, E. A., Zellers, S. M., Bierut, L. J., Buchwald, J., Copeland, W. E., Corley, R. P., Friedman, N. P., Foroud, T. M., Gillespie, N. A., Gizer, I. R., Heath, A. C., Hickie, I. B., Kaprio, J., Keller, M. C., Lee, J. J., Lind, P., Madden, P. A., Maes, H. H. M., Martin, N. G., McGue, M., Medland, S. E., Nelson, E. C., Pearson, J., Porjesz, B., Stallings, M. C., Vrieze, S., Wilhelmson, K. C., Kranzler, H. R., Walters, R. K., Polimanti, R., Malison, R., Zhou, H., Stefansson, K., Sanchez-Roige, S., Potenza, M., Mutirangura, A., Shotelersuk, V., Kalayasiri, R., Edenberg, H. J., Gelernter, J. and Agrawal, A. (2025). Multi-ancestral genome-wide association study of clinically defined nicotine dependence reveals strong genetic correlations with other substance use disorders and health-related traits. Psychol Med, e234. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40831304


Siembida, E. J., Greene, B., Oh, E. J., Wiseman, K. P., Basile, M., Vadhan, N. P. and Diefenbach, M. A. (2025). Tobacco and other substance co-use among adolescents and young adults with cancer who use tobacco: prevalence and associations with nicotine dependence and depression. Fam Med Community Health, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40819909


Hulsmans, D. H. G., Dieleman, J., Kleinjan, M., Luijten, M. and Otten, R. (2025). Temporal effects of environmental tobacco smoke exposure: An ecological momentary assessment study among adolescent never- and experimental smokers. Addict Behav, 108379. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40347563


Yang, H., Cheng, A., Zhu, D., Zhao, M. and Xi, B. (2025). Childhood Smoking Initiation, Genetic Susceptibility, and Incident Cardiovascular Diseases in Adulthood. J Adolesc Health. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40382723


Chenoweth, M. J., Lerman, C., Knight, J. and Tyndale, R. F. (2025). Sex dependent genetic architecture of biochemically verified tobacco use. Psychiatry Res, 116465. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40174410


Yang, L., Li, J., Chen, Y., Wei, Y., Song, C., Zhang, J., Dai, L., Shi, Y., Xiong, Z., Shan, Y. and Huang, X. (2025). Association between maternal smoking during pregnancy and smoking behaviors in adult offspring. Front Public Health, 1505418. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40226319


Maraqa, B., Abu Mayaleh, M., Arafeh, S., Altell, K., Khleif, A., Najjar, A. and Abu-Radwan, B. (2025). Secondhand Smoke Exposure and Smoking Attitudes and Behaviors Among Adolescents in the Gaza Strip: Findings From the 2019 Global Youth Tobacco Survey. Tob Use Insights, 1179173X251314649. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39830674


Agbaje, A. O. (2024). Accelerometer-based sedentary time and physical activity with incident and progressive tobacco smoking in 2503 children: A 13-year mediation and temporal longitudinal study. Behav Res Ther, 104674. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39733609


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2