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7.21 Lung cancer screening and biomedical risk assessments
Foreword

Relevant news and research: Lung cancer screening and biomedical risk assessments

Bernstein, E. L., Bade, B. C., DeRycke, E. C., Lerz, K., Zeghlache, R., Rose, M., Kravetz, J., Farmer, M. M., Bastian, L., Akgun, K. M. and Cain, H. C. (2025). The Association Between Sex and Lung Cancer Screening Adherence to Follow-Up in a Cohort of Veterans. J Womens Health (Larchmt). Available from: https://www.ncbi.nlm.nih.gov/pubmed/40045919


Bhamani, A., Creamer, A., Verghese, P., Prendecki, R., Horst, C., Tisi, S., Hall, H., Khaw, C. R., Mullin, M., McCabe, J., Gyertson, K., Bowyer, V., Arancon, D., Eng, J., Bojang, F., Levermore, C., Hacker, A. M., Arthur-Darkwa, E., Farrelly, L., Patel, A., Lock, S., Shaw, A., Banka, R., Bhowmik, A., Ekeowa, U., Mangera, Z., Valerio, C., Ricketts, W. M., Mohammed, A., O'Shaughnessy, T., Navani, N., Quaife, S. L., Nair, A., Devaraj, A., consortium, S., Dickson, J. L., Hackshaw, A. and Janes, S. M. (2025). Low-dose CT for lung cancer screening in a high-risk population (SUMMIT): a prospective, longitudinal cohort study. Lancet Oncol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40154514


Conahan, P., Robinson, L. A., Le, T., Valdes, G., Schabath, M. B., Byrne, M. M., Green, L., El Naqa, I. and Luo, Y. (2025). EEC-GIFT: a fairness-aware machine learning framework for lung cancer screening eligibility using real-world data. JNCI Cancer Spectr. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40111867


Ghirotto, L., Paci, E., Bricci, C., Marini, S., Bessi, V., Diaz Crescitelli, M. E., Rondini, E., Pistelli, F., Gorini, G., Bosi, S., Giorgi Rossi, P. and Working, G. (2025). Self-blaming as a barrier to lung cancer screening and smoking cessation programs in Italy. A qualitative study. PLoS One, 3, e0318732. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40043010


Hwang, H. A., Kim, D. J., Yoon, N. H., Jun, J. K., Suh, M., Lee, S., Kim, S., Jung, S. E. and Lee, H. (2025). Preliminary reports of lung cancer screening with low-dose computed tomography: a nationwide performance on the Korean population in 2019-2020. Eur Radiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40042649


Jung, J., Razzak, E., Avenido, A. R., Rashidi, A., Jia, S., Tran, N. Q., Yao, R., Nguyen, E. L., Bernaba, A., Echeverria, R., Nguyen, T. Q., Imanzadeh, A. and Sadigh, G. (2025). Patient-Reported Barriers and Preferred Interventions to Improve Lung Cancer Screening Uptake. J Am Coll Radiol, 3, 269-279. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40044305


Kcomt, L., Jardine, J., Evans-Polce, R. J., McCabe, S. E., Clift, J., Walter-McCabe, H., Engstrom, C. W. and Veliz, P. T. (2025). Associations of Sexual Orientation and Sexual Orientation-Related State Policy Environments with Smoking and Lung Cancer Screening Outcomes among U.S. Adults. Nicotine Tob Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40163704


Kim, R. Y., Rendle, K. A., Mitra, N., Neslund-Dudas, C., Greenlee, R. T., Honda, S. A., Schapira, M. M., Simoff, M. J., Jeon, J., Meza, R., Ritzwoller, D. P. and Vachani, A. (2025). Adherence to Annual Lung Cancer Screening and Rates of Cancer Diagnosis. JAMA Netw Open, 3, e250942. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40100218


Laisaar, T., Kallavus, K., Poola, A., Rappo, M., Taur, M., Makke, V., Frik, M., Ilves, P. and Laisaar, K. T. (2025). Population-based systematic enrolment of individuals ensures high lung cancer screening uptake. Cancer Treat Res Commun, 100889. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40031097


Liu, B., Halpern, M. T., Doria-Rose, V. P., Croswell, J. M., Lee, R. and Feuer, E. J. (2025). Lung cancer screening rates in the United States: Contribution of the 2020 NHIS estimates to national and state level trends. Am J Prev Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40157465


Mulshine, J. L., Avila, R. S., Sylva, M., Aldige, C., Blum, T., Cham, M., de Koning, H. J., Fain, S. B., Field, J., Flores, R., Giger, M. L., Gipp, I., Grannis, F. W., Gratama, J. W. C., Healton, C., Kazerooni, E. A., Kelly, K., Lancaster, H. L., Montuenga, L. M., Myers, K. J., Naghavi, M., Osarogiagbon, R., Pastorino, U., Pyenson, B. S., Reeves, A. P., Rizzo, A., Ross, S., Schneider, V., Seijo, L. M., Shaham, D., Smith, R., Taoli, E., Tenhaaf, van der Aalst, C. M., Viola, L., Vogel-Claussen, J., Walstra, A. N. H., Wu, N., Yang, P. C., Yip, R., Oudkerk, M., Henschke, C. I. and Yankelelvitz, D. F. (2025). AI integrations with lung cancer screening: Considerations in developing AI in a public health setting. Eur J Cancer, 115345. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40090215


Pagano, T. A. and Hanif, M. K. (2025). Nurse-Led Tobacco Cessation for Veterans Using Motivational Interviewing in a Lung Cancer Screening Program. Clin J Oncol Nurs, 2, 130-134. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40096569


Park, E. R., Haas, J. S., Rigotti, N. A., Neil, J. M., Marotta, C. J., Wint, A. J., Gonzalez, I., McGovern, S. E., Chang, Y., Levy, D. E., Flores, E. J., Merker, V. L., Noonan, E. and Bliss, C. C. (2025). Integrating Tobacco Treatment Into Lung Cancer Screening: The Screen Assist Factorial Randomized Clinical Trial. JAMA Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40029643


Pitrou, I., Petrangelo, A., Besson, C., Pepe, C., Waschke, A. H., Agulnik, J., Gonzalez, A. V. and Ezer, N. (2025). Lung Cancer Screening in Family Members and Peers of Patients With Lung Cancer: Protocol for a Prospective Cohort Study. JMIR Res Protoc, e58529. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40153794


Rankin, N. M. (2025). Lung Cancer Screening Uptake and Psychological Outcomes: Are We Closer to Understanding How Communication Impacts on Distress and Regret?. Chest, 3, 652-653. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40074485


Romeikat, N. L., Sullivan, F., Daly, F. and Kong, W. (2025). The Importance of Comorbidities at Baseline and 5-Year Follow-Up in a Lung Cancer Biomarker Screening Trial. J Clin Med, 6. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40142924


Ryan, L. C., Choudhary, S., Kapula, N., Kang, A., Shula, L. G., Elliott, I. A., Guenthart, B. A., Liou, D. Z., Backhus, L. M., Berry, M. F., Shrager, J. B. and Lui, N. S. (2025). Community Awareness of Lung Cancer Screening: A Cross-Sectional Survey. Ann Thorac Surg Short Rep, 1, 113-117. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40098881


Tailor, T. D., Gutman, R., An, N., Hoffman, R. M., Chiles, C., Carlos, R. C., Sicks, J. D. and Gareen, I. F. (2025). Positive Screens Are More Likely in a National Lung Cancer Screening Registry Than the National Lung Screening Trial. J Am Coll Radiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40023436


Wang, H., Cheeti, R., Murray, M., Muirheid, T. A., McDowell, J. and Sambamoorthi, U. (2025). Identifying lung cancer in Emergency Department patients outside national lung cancer screening guidelines. J Thorac Dis, 2, 695-706. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40083500


Wilshire, C. L., Buehler, K. E., Henson, C. A., Gilbert, C. R. and Gorden, J. A. (2025). Community-Based Lung Cancer Screening Program Structure, Quality, and Barriers: The Struggle for Implementation. Can Respir J, 9683951. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40161856


Young, C. D., Katki, H. A., Cheung, L. C., Rivera, M. P., Robbins, H. A., Aldrich, M. C., Blume, J. D., Chaturvedi, A. K. and Landy, R. (2025). Individual- and Group-Level Disparities Between Racial and Ethnic Groups in Lung Cancer Screening Eligibility Criteria. JAMA Netw Open, 3, e252172. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40146107


Bhamani, A., Katsampouris, E., Bojang, F., Verghese, P., Creamer, A., Prendecki, R., Khaw, C. R., Dickson, J. L., Horst, C., Tisi, S., Hall, H., McCabe, J., Gyertson, K., Hacker, A. M., Farrelly, L., Navani, N., Hackshaw, A., Consortium, S., Janes, S. M. and Quaife, S. L. (2025). Uptake and 4-week outcomes of an 'opt-out' smoking cessation referral strategy in a London-based lung cancer screening setting. BMJ Open Respir Res, 1. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39915257


Cui, Y. (2025). Secondhand Smoke in Low-Risk Groups: A Hidden Danger in Lung Cancer Screening. J Thorac Oncol, 2, e33-e34. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39914932


Koster, K. M., Feinberg, A., Sigel, K., Wisnivesky, J., Smith, C. and Kale, M. (2025). Real-World Smoking History Documentation and Identification of Lung Cancer Screening Candidates. Am J Respir Crit Care Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39918855


Munpolsri, P., Su, C. W., Chen, S. L. and Yen, A. M. (2025). Behavior Changes for Smokers and Betel Quid Chewers Participating in the Organized Oral Mucosal Screening Between 2010 and 2021 in Taiwan. Cancers (Basel), 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39941766


Parums, D. V. (2025). Editorial: Current Approaches to Screening for Lung Cancer in Smokers and Non-Smokers. Med Sci Monit, e948255. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39891449


Pestka, D. L., Campbell, M. E., Schmulewitz, N. A. and Melzer, A. C. (2025). Barriers to Integrating Tobacco Dependence Treatment into Lung Cancer Screening: A Qualitative Assessment. J Prim Care Community Health, 21501319251321608. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39993144


Silvestri, G. A., Young, R., Tanner, N. T. and Mazzone, P. (2025). A Response to the Letter to the Editor: "Secondhand Smoke in Low-Risk Groups: A Hidden Danger in Lung Cancer Screening". J Thorac Oncol, 2, e34. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39914933


Bell-Williams, R., Bains, M., Thorley, R., Dowd, E. O., Baldwin, D. and Murray, R. (2025). Increasing lung screening uptake: Exploring people who smoke and their family members' concerns and recommendations regarding screening invitations. Tob Prev Cessat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39801659


Cinciripini, P. M., Minnix, J. A., Kypriotakis, G., Erasmus, J., Beneventi, D., Karam-Hage, M., Carpenter, K., Volk, R. J., Carter, B., Godoy, M. C. B., Strange, C., Shih, Y. T., Cui, Y., Green, C. E. and Robinson, J. D. (2025). Smoking Cessation Interventions in the Lung Cancer Screening Setting: A Randomized Clinical Trial. JAMA Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39804633


Prochaska, J. J. (2025). Treating Tobacco Use Within Lung Cancer Screening Programs Is Optimal. JAMA Intern Med. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39804653


Yoon, N. Y., Seo, M., Lee, N. and Kim, Y. (2025). Factors Associated with Smoking Cessation of Participants in the National Lung Cancer Screening Program in Korea. Cancer Res Treat. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39810490


Avila, J. C., Flores, E. J., Su, Y. J., Haas, J. S., Park, E. R. and Rigotti, N. A. (2024). Association of individual and neighborhood socioeconomic status with outcomes of a smoking cessation intervention provided in the lung cancer screening setting. Prev Med, 108207. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39694102


Flyckt, R. N. H., Sjodsholm, L., Henriksen, M. H. B., Brasen, C. L., Ebrahimi, A., Hilberg, O., Hansen, T. F., Wiil, U. K., Jensen, L. H. and Peimankar, A. (2024). Pulmonologists-level lung cancer detection based on standard blood test results and smoking status using an explainable machine learning approach. Sci Rep, 1, 30630. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39719477


Rogova, A., Lowenstein, L. M., Reitzel, L. R., Casey, K. and Volk, R. J. (2024). Missed Opportunities for Lung Cancer Screening among Behavioral Health Patients with Elevated Cigarette Smoking Rates: Lung Cancer Screening and Behavioral Health. Chest. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39674344


Shusted, C. S., Mukhtar, S., Lee, J., Ruane, B., Muse, E., Emeigh-McBride, L., Gatson-Anderson, E., Kane, G. C., Wen, K. Y., Juon, H. S. and Barta, J. A. (2024). Factors Associated With Receipt of Tobacco Treatment Integrated With Nurse Navigation in a Centralized Lung Cancer Screening Program at an Urban Academic Medical Center. Cancer Control, 10732748241304966. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39653391


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2