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3.16 Smoking and diabetes
Foreword

Relevant news and research: Smoking and diabetes

He, Y., Ye, Y., Liu, M., Xing, B., Xu, H., He, J., Mai, W., Qin, S., Luo, Z., Xu, Y. and Wang, X. (2026). Global burden of deaths and DALYs attributable to smoking in Middle-Aged and elderly patients with type 2 Diabetes, 1990-2021: A systematic analysis of the GBD 2021 study. Endocrine, 1, 45. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41563647


Bader, S., Hasan, S., Magliano, D. J., Islam, R. M., Palawaththa, S., Romero, L. and Karim, M. N. (2025). The association between smoking and diabetic neuropathy: a systematic review and meta-analysis. Syst Rev, 1, 249. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41444672


Campuzano, J. C., Rodriguez, J. M., Reynales, L. M., Hernandez, A. and Urrego, D. C. (2025). Population Attributable Fraction of Tobacco Use and Type 2 Diabetes Mellitus: An Analysis of the ENSANUT 2021. Epidemiologia (Basel), 4. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41439842


He, Y., Lai, C., Xing, B., Xu, H., He, J., Mai, W., Qin, S., Wang, J. and Ye, Y. (2025). Trends in type 2 diabetes-related deaths and disability-adjusted life years among smoking middle-aged and elderly adults in China, 1990-2021. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41357961


Hussain, Z. S., Loya, A., Muayad, J., Chauhan, M. Z. and Sallam, A. B. (2026). The Influence of Smoking, Cessation Measures, and Other Substances on Progression of Diabetic Retinopathy in Type 2 Diabetes. Ophthalmic Surg Lasers Imaging Retina, 1, 39-45. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41401372


Zeng, Z. and Guo, J. (2025). Interaction between Overweight, Obesity and Smoking on the Risk of Pre-Diabetes and Type 2 Diabetes in Guangdong, China. Iran J Public Health, 9, 1894-1905. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41277925


Zhang, S., Zhao, L. and Li, J. (2025). Maternal smoking during pregnancy and risk of childhood-onset type 1 diabetes in offspring: A systematic review and meta-analysis. Biomol Biomed. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41212794


Bader, S., Hasan, S., Islam, R. M., Abdulrazak, G., Al Zarouni, K., Muayyad, M. and Karim, M. N. (2025). Assessing the Risk of Peripheral Neuropathy Among Male Tobacco Smokers With Type 2 Diabetes: A Matched Case-Control Study. J Prim Care Community Health, 21501319251368607. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41157992


Yu, Y., Li, Y., Nguyen, T. T., Yue, D., Tchangalova, N., Flouton, C. E. and Liu, H. (2025). Association between smoking cessation and risk for type 2 diabetes, stratified by post-cessation weight change: A systematic review and meta-analysis. Prev Med, 108429. Available from: https://www.ncbi.nlm.nih.gov/pubmed/41077255


Leavens, E. L. S., Arnold, M. J., Nollen, N. L., Sanderson Cox, L., Brown, K. A. and Ellerbeck, E. F. (2025). GLP-1 Receptor Agonist Indications and Prescriptions Among Adults Who Do and Do Not Smoke. Diabetes Care. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40986636


Cho, S. H., Kim, G., Lee, K. N., Oh, R., Kim, J. Y., Jang, M., Lee, Y. B., Jin, S. M., Hur, K. Y., Han, K. and Kim, J. H. (2025). Impact of smoking and physical activity on cardiovascular outcomes in type 2 diabetes across steatotic liver disease categories. Sci Rep, 1, 31029. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40849338


Paz-Graniel, I., Kose, J., Duquenne, P., Babio, N., Salas-Salvado, J., Hercberg, S., Galan, P., Touvier, M., Fezeu, L. K. and Andreeva, V. A. (2025). Alcohol, Smoking, and Their Synergy as Risk Factors for Incident Type 2 Diabetes. Am J Prev Med, 5, 108011. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40752888


Alrikabi, N. H., Chemingui, H., Soheir, N. A. E.-R. and Madiha, K. (2025). Impact of smoking and environmental toxins on diabetic retinopathy: role of trace elements, lipid profiles, and vitamin A. Cell Mol Biol (Noisy-le-grand), 7, 92-101. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40736288


Gu, P., Zheng, S., Zhang, S., Yuan, J., Hong, H., Dai, J., Zhao, J., Xu, K., Yang, T., Fu, Q., Shen, S. and Dai, H. (2025). Gene-Smoking Interaction in Insulin Sensitivity and beta-Cell Function Among Normal Glucose Tolerance Individuals. J Diabetes, 7, e70131. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40719081


Jeong, C., Kim, B., Oh, D. J., Sohn, T. S., Han, K. and Kwon, H. S. (2025). Association between smoking status and suicide mortality in patients with type 2 diabetes: A nationwide population-based cohort study. Diabetes Metab, 101692. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40721191


Park, J. H., Hong, J. Y., Han, K. and Shen, J. J. (2025). Sex-Specific Associations of Glycemic Status and Smoking with Bladder Cancer Risk: A Nationwide Cohort Study. Cancers (Basel), 13. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40647559


Vanderlinden, L. A., Wong, E., Johnson, R. K., Carry, P., Dong, F., Kechris, K., Rewers, M. and Norris, J. M. (2025). DNA Methylation Smoking Scores and Risk of Islet Autoimmunity and Type 1 Diabetes. Diabetes Care. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40712097


Wu, Y. Y., Zhang, W., Woodworth, F. and Mattheus, D. (2025). Smoking modifies the effect of diabetes on severe tooth loss: Cross-sectional analysis of Hawai'i BRFSS data from 2012 to 2020. Asia Pac J Public Health, 1.0154E+16. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40586244


Yeom, S. and Yang, Y. (2025). Impact of smoking on diabetes complications: a secondary analysis of the Korean National Health Insurance Service-health screening cohort (2002-2019). J Korean Acad Nurs, 2, 222-235. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40468668


Yook, H. J., Kim, E., Kim, Y. H., Lee, G. N., Han, K. and Lee, J. H. (2025). A link between smoking behaviors and the risk of hidradenitis suppurativa in diabetic patients. PLoS One, 6, e0325357. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40472049


Plaitano, E. G. and Stanger, C. (2025). Joint effect of nicotine use and diabetes distress on glycemic control in young adults with type 1 diabetes. J Diabetes Complications, 8, 109083. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40398346


Reed, Z. E., Sallis, H. M., Richmond, R. C., Attwood, A. S., Lawlor, D. A. and Munafo, M. R. (2025). Investigating whether smoking and alcohol behaviours influence risk of type 2 diabetes using a Mendelian randomisation study. Sci Rep, 1, 7985. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40055374


Mahesh, B. and Manjegowda, N. (2024). Comparing the Doppler flow parameters of orbital vessels among healthy nonsmokers, diabetic nonsmokers, and diabetic smokers visiting a tertiary health-care center. Taiwan J Ophthalmol, 4, 594-601. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39803404


Shams, R. B. and Sayed, C. J. (2025). Hidradenitis Suppurativa Surgery Complication Rates Among Patients With Obesity or Diabetes or Who Smoke: A Review. JAMA Dermatol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39879067


Tsukinoki, R., Murakami, Y., Hayakawa, T., Kadota, A., Harada, A., Kita, Y., Okayama, A., Miura, K., Okamura, T. and Ueshima, H. (2025). Comprehensive assessment of the impact of blood pressure, body mass index, smoking, and diabetes on healthy life expectancy in Japan: NIPPON DATA90. J Epidemiol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39805597


Wang, B., Li, H., Ma, H. and Chen, Z. (2024). The association of cigarette smoking with the development and progression of diabetic retinopathy: based on cross-sectional survey and mendelian randomization. J Transl Med, 1, 1169. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39741329


Xiong, H., Zhao, P., Ma, F., Tang, D. and Liu, D. (2025). The effects of interaction between smoking and abdominal obesity on pre-diabetes mellitus. Sci Rep, 1, 1332. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39779809


Cho, M. H., Jung, J., Koo, H. Y., Jung, W., Han, K., Cho, I. Y. and Shin, D. W. (2024). Effects of Smoking Behavior Change on Diabetes Incidence after Cancer Development: A Nationwide Cohort Study. Diabetes Metab, 101604. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39709168


McLaughlin, D., Sasaki, M., Hoffmann, C., Brewster, L. and K, E. H. (2024). Smoking Status Impacts Mitochondrial Function and Synthetic Function in Mesenchymal Stem Cells Derived from Diabetics with Arterial Insufficiency. Adv Wound Care (New Rochelle). Available from: https://www.ncbi.nlm.nih.gov/pubmed/39706587


Sebastian-Valles, F., Hernando Alday, I., Tapia-Sanchiz, M. S., Raposo-Lopez, J. J., Garai Hierro, J., Navas-Moreno, V., Martinez-Alfonso, J., Arranz Martin, J. A., Sampedro-Nunez, M. A. and Marazuela, M. (2024). Association of smoking with the efficacy of continuous glucose monitoring in type1 diabetes: A propensity score-matched cohort study. Med Clin (Barc). Available from: https://www.ncbi.nlm.nih.gov/pubmed/39709280


Sebastian-Valles, F., Martinez-Alfonso, J., Navas-Moreno, V., Arranz-Martin, J. A., Tapia-Sanchiz, M. S., Raposo-Lopez, J. J., Sampedro-Nunez, M. A., Martinez-Vizcaino, V. and Marazuela, M. (2025). Influence of smoking on glycaemic control in individuals with type 1 diabetes using flash glucose monitoring and its mediating role in the relationship between socioeconomic status and glycaemic control. J Diabetes Metab Disord, 1, 11. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39697858


Zhu, H., Li, L., Liu, S. and Li, J. (2024). Smoking and diabetic nephropathy: An updated systematic review and meta-analysis. J Diabetes Investig. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39728025


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2