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3.4 Lung cancer
Foreword

Relevant news and research: Lung cancer

Islami, F., Nargis, N., Liu, Q., Bandi, P., Siegel, R. L., Choudhury, P. P., Freedman, N. D., Warner, K. E. and Jemal, A. (2025). Averted lung cancer deaths due to reductions in cigarette smoking in the United States, 1970-2022. CA Cancer J Clin. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40131130


Korde, A., Ramaswamy, A., Anderson, S., Jin, L., Zhang, J. G., Hu, B., Velasco, W. V., Diao, L., Wang, J., Pisani, M. A., Sauler, M., Boffa, D. J., Puchalski, J. T., Yan, X., Moghaddam, S. J. and Takyar, S. S. (2025). Cigarette smoke induces angiogenic activation in the cancer field through dysregulation of an endothelial microRNA. Commun Biol, 1, 511. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40155749


Ouyang, C., Yu, X., Wang, H. and Zeng, P. (2025). Multidimensional bioinformatics perspective on smoking-linked driver genes and immune regulatory mechanisms in non-small cell lung cancer. J Transl Med, 1, 330. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40087674


Wang, R., Zhang, Z., Shan, X., Dong, J., Yang, X., Zhang, J. and Cao, J. (2025). Tobacco-related lung cancer burden in the Western Pacific Region from 1990 to 2021: An age-period-cohort analysis from the Global Burden of Disease Study. Tob Induc Dis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40083560


Yamamoto, S., Koyanagi, Y. N., Iwashita, Y., Shinozaki, T., Fujiwara, Y., Sakakura, N., Hara, M., Nishida, Y., Otonari, J., Ikezaki, H., Tanoue, S., Koriyama, C., Kasugai, Y., Oze, I., Koyama, T., Tomida, S., Michihata, N., Nakamura, Y., Suzuki, S., Nakagawa-Senda, H., Nagayoshi, M., Kubo, Y., Kato, Y., Wakai, K., Watanabe, T., Ishizu, M., Takashima, N., Kadota, A., Momozawa, Y., Nakatochi, M., Tamura, T., Niimi, A., Ito, H. and Matsuo, K. (2025). Manuscript Smoking Behavior-related Genetic Variants and Lung Cancer Risk in Japanese: an Assessment by Mediation Analysis. Carcinogenesis. Available from: https://www.ncbi.nlm.nih.gov/pubmed/40059777


Deng, X., Zhang, H., Wang, Y., Ma, D. and Wu, Q. (2025). Exploring Potential Associations between Benzo[a]pyrene, Nicotine Exposure, and Lung Cancer: Molecular Insights, Prognostic Biomarkers, and Immune Cell Infiltration. Chem Res Toxicol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39980136


Leo, F., Migliaretti, G., Sobrero, S., Angelescu, D., Mc Bride, T., Dahan, M., Jougon, J. and Societe Francaise De Chirurgie Thoracique Et Cardiovasculaire, S. (2025). Impact of smoking habits on the postoperative outcome following lung surgery for cancer: results from the Epithor database. Eur J Cardiothorac Surg. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39977368


Burt, J. R., Qaqish, N., Stoddard, G., Jridi, A., Anderson, P. S., Woods, L., Newman, A., Carter, M. R., Ellessy, R., Chamberlin, J. and Kabakus, I. (2025). Non-small cell lung cancer in ever-smokers vs never-smokers. BMC Med, 1, 3. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39757150


Cayuela, L., Gaeta, A. M., Piury-Pinzon, J., Ortega-Calvo, M. and Cayuela, A. (2025). Changing Patterns of Lung Cancer Mortality in Andalusia: Insights From Age-period-cohort Analysis and Historical Smoking Trends. Open Respir Arch, 1, 100390. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39758958


Yamamoto, H., Shirasawa, M. and Naoki, K. (2025). Analysis of lung cancer incidence, mortality trends, and smoking rates in Japan:1975-2022 with insights on the impact of COVID-19. Int J Clin Oncol, 2, 199-209. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39821472


Aggarwal, R. K., Sidoli, S., Wang, J., Sahu, S., Sanawar, R., Gupta, V., Aluri, S., Sukrithan, V., Vegivinti, C. T. R., Zavras, P. D., Verma, D., Gordon-Mitchell, S., Agarwal, B., Verma, T., Starczynowski, D. T., Steidl, U. G., Shastri, A., Halmos, B., LaFave, L. M., Cheng, H., Verma, A. and Zou, Y. (2024). Smoking carcinogen induced inflammation promotes lung carcinogenesis via IRAK4 activation. Clin Cancer Res. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39704655


Chen, L., Wang, X., Xie, N., Zhang, Z., Xu, X., Xue, M., Yang, Y., Liu, L., Su, L., Bjaanaes, M., Karlsson, A., Planck, M., Staaf, J., Helland, A., Esteller, M., Christiani, D. C., Chen, F. and Zhang, R. (2024). A two-phase epigenome-wide four-way gene-smoking interaction study of overall survival for early-stage non-small cell lung cancer. Mol Oncol. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39630602


Zhang, J., Tang, J., Yang, R., Chen, S., Jian, H. and Zeng, P. (2024). The Global, Regional, and National Burden of Tracheal, Bronchus, and Lung Cancer Caused by Smoking: An Analysis Based on the Global Burden of Disease Study 2021. Ann Glob Health, 1, 77. Available from: https://www.ncbi.nlm.nih.gov/pubmed/39650717


Earlier news and research

For news items and research on this topic earlier than 2025, click here.

Intro
Chapter 2